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认知因素在强迫症状发病机制中的作用:一项前瞻性研究。

The role of cognitive factors in the pathogenesis of obsessive-compulsive symptoms: a prospective study.

作者信息

Abramowitz Jonathan S, Khandker Maheruh, Nelson Christy A, Deacon Brett J, Rygwall Rebecca

机构信息

Mayo Clinic OCD/Anxiety Disorders Program, 200 First Street SW, Rochester, MN, USA.

出版信息

Behav Res Ther. 2006 Sep;44(9):1361-74. doi: 10.1016/j.brat.2005.09.011. Epub 2005 Dec 13.

Abstract

Cognitive models of obsessive-compulsive disorder (OCD) posit that specific kinds of dysfunctional beliefs (e.g., pertaining to responsibility and the significance of intrusive thoughts) underlie the development of this disorder. The present study was designed to prospectively evaluate whether dysfunctional beliefs thought to underlie OCD act as a specific vulnerability factor in the pathogenesis of obsessive-compulsive symptomatology. Eighty-five individuals were prospectively followed over a period of time thought to be associated with an increased onset of OCD symptoms -- childbirth and the postpartum. The majority of these new mothers and fathers experienced intrusive infant-related thoughts and performed neutralizing behaviors similar to, but less severe than, those observed in OCD. Scores on a measure of dysfunctional beliefs thought to underlie OCD predicted the development of obsessive-compulsive symptoms after controlling for pre-existing OCD symptoms, anxiety, and depression. Dysfunctional beliefs also predicted the severity of checking, washing, and obsessional OCD symptom dimensions, but not neutralizing, ordering, or hoarding symptom dimensions. These data provide evidence for specific dysfunctional beliefs as risk factors in the development of some types of OCD symptoms.

摘要

强迫症(OCD)的认知模型认为,特定类型的功能失调信念(例如,与责任及侵入性思维的重要性相关的信念)是该障碍发展的基础。本研究旨在前瞻性评估被认为是强迫症基础的功能失调信念是否在强迫症状的发病机制中作为一种特定的易感性因素。八十五名个体在一段被认为与强迫症症状发作增加相关的时间内——分娩期和产后——接受了前瞻性随访。这些新妈妈和新爸爸中的大多数都经历了与婴儿相关的侵入性思维,并表现出与强迫症中观察到的类似但程度较轻的中和行为。一项被认为是强迫症基础的功能失调信念量表的得分,在控制了先前存在的强迫症症状、焦虑和抑郁后,预测了强迫症状的发展。功能失调信念还预测了检查、洗涤和强迫观念等强迫症症状维度的严重程度,但不能预测中和、整理或囤积症状维度。这些数据为特定的功能失调信念作为某些类型强迫症症状发展的风险因素提供了证据。

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