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厌恶敏感性递增特异性在强迫症症状预测中的作用:横断面和前瞻性研究。

Incremental specificity of disgust sensitivity in the prediction of obsessive-compulsive disorder symptoms: Cross-sectional and prospective approaches.

机构信息

Vanderbilt University, Nashville, Tennessee 37203, United States.

出版信息

J Behav Ther Exp Psychiatry. 2009 Dec;40(4):533-43. doi: 10.1016/j.jbtep.2009.07.004. Epub 2009 Jul 29.

DOI:10.1016/j.jbtep.2009.07.004
PMID:19683221
Abstract

The present study examines the association between disgust sensitivity (DS) and obsessive-compulsive disorder (OCD) symptoms in two non-clinical samples. Findings from Study 1 (n=270) revealed a significant association between DS and OCD symptoms even after controlling for negative affect and anxiety sensitivity. Subsequent analysis also revealed a specific association between DS and the washing subtype of OCD symptoms when controlling for other OCD symptom dimensions. DS did not significantly predict residual change in total symptoms of OCD over a 12-week period (n=300) when controlling for risk factors for anxiety disorder symptoms in general (e.g., negative affect, anxiety sensitivity) and OCD specifically (e.g., obsessive beliefs) in Study 2. However, exploratory analyses suggest that DS may be predictive of residual change in some OCD symptom subtypes but not others. Implications of these findings for future research on the role of disgust in OCD are discussed.

摘要

本研究考察了在两个非临床样本中,厌恶敏感性(DS)与强迫症(OCD)症状之间的关联。研究 1(n=270)的结果表明,即使在控制了负面情绪和焦虑敏感性后,DS 与 OCD 症状之间仍存在显著关联。后续分析还表明,在控制其他 OCD 症状维度后,DS 与 OCD 症状的洗涤亚型之间存在特定关联。在研究 2 中,当控制一般焦虑障碍症状的风险因素(例如,负面情绪、焦虑敏感性)和 OCD 特定风险因素(例如,强迫观念)时,DS 并没有显著预测 OCD 总症状在 12 周内的残留变化(n=300)。然而,探索性分析表明,DS 可能对某些 OCD 症状亚型的残留变化具有预测性,但对其他亚型则没有。这些发现对未来研究厌恶在 OCD 中的作用具有启示意义。

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