Habel A, Elhadi N, Sommerlad B, Powell J
North Thames Cleft Lip and Palate Centre, Great Ormond Street Hospital for Children, UK.
Arch Dis Child. 2006 Mar;91(3):238-40. doi: 10.1136/adc.2005.077958. Epub 2005 Dec 13.
To identify prevalence of delayed detection of cleft palate, and associated factors that could lead to improved identification at neonatal clinical examination.
Audit of hospital notes, parental questionnaire incorporating open ended questions, and telephone questionnaire of junior doctors in the referring hospitals incorporating fixed choice questions.
Of 344 cleft palate patients without cleft lip or submucous cleft palate, the day the cleft was detected was recorded in 92%. Delayed detection, after the first day, was 28% overall, distributed as 37% with isolated cleft palate and 23% with syndromic cleft palate. Narrow V shaped clefts were more likely to be delayed in detection compared with broad U shaped clefts, as were soft palate clefts compared with hard palate clefts. Five with isolated cleft palates were not detected until after the first year. Babies born at home were unlikely to be detected on day 1. Symptoms were significantly increased in the delayed detection group for feeding problems and nasal regurgitation. A telephone questionnaire of trainee paediatricians in referring units revealed that digital examination was more commonly practised than visual inspection, and few recalled receiving specific instruction on examination of the palate.
Delayed detection of cleft palate was not uncommon, and the features of those more likely to be missed suggested digital examination was related. Trainee doctors and midwives should be instructed to inspect visually using a light and tongue depressor, then digitally if submucous cleft palate is suspected.
确定腭裂延迟诊断的发生率,以及在新生儿临床检查中可能有助于改善诊断的相关因素。
审查医院病历、包含开放式问题的家长问卷,以及向转诊医院的初级医生发放的包含选择题的电话问卷。
在344例无唇裂或黏膜下腭裂的腭裂患者中,92%记录了腭裂被发现的日期。总体而言,第一天之后的延迟诊断率为28%,其中孤立性腭裂的延迟诊断率为37%,综合征性腭裂为23%。与宽U形腭裂相比,窄V形腭裂更有可能延迟诊断,软腭裂与硬腭裂相比也是如此。5例孤立性腭裂患者直到一岁以后才被发现。在家出生的婴儿不太可能在出生第一天被诊断。延迟诊断组中喂养问题和鼻反流的症状明显增加。对转诊单位的儿科实习医生进行的电话问卷调查显示,手指检查比视诊更常用,很少有人记得接受过关于腭部检查的具体指导。
腭裂延迟诊断并不罕见,那些更容易被漏诊的特征表明与手指检查有关。应指导实习医生和助产士先用灯光和压舌板进行视诊,若怀疑有黏膜下腭裂则再进行手指检查。