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胎儿超声和磁共振成像在迁移障碍产前诊断中的作用

Role of fetal ultrasound and magnetic resonance imaging in the prenatal diagnosis of migration disorders.

作者信息

Rubod Chrystèle, Robert Yann, Tillouche Nadia, Devisme Louise, Houfflin-Debarge Véronique, Puech Francis

机构信息

Clinique de Gynécologie Obstétrique, Hôpital Jeanne de Flandre, CHRU de Lille, France.

出版信息

Prenat Diagn. 2005 Dec;25(13):1181-7. doi: 10.1002/pd.1133.

DOI:10.1002/pd.1133
PMID:16353281
Abstract

OBJECTIVES

To evaluate the contribution and limitations of fetal ultrasonography (US) and magnetic resonance imaging (MRI) for the diagnosis and management of migration disorders.

METHODS

Over a 5-year period, 14 fetuses with pathological migration disorders, without an infectious context, were taken care of in our centre. All underwent US; nine underwent MRI as well. Sonographic and MRI data were compared with neuropathological data.

RESULTS

The diagnosis of gyral disorders was obtained by US in 1/14 cases; other cerebral abnormalities were found suggesting neuronal disorder in the remainder. Cerebral MRI suggested gyral abnormality in eight of the nine cases.

CONCLUSIONS

US performance is increasing. MRI appears to be a promising method for the diagnosis of fetal migration disorders, giving better results than US. It may be recommended in cases of abnormal cerebral US findings or familial clinical history. However, interpretation of MRI can be tricky and the resulting diagnosis occurs late within the pregnancy.

摘要

目的

评估胎儿超声检查(US)和磁共振成像(MRI)在迁移障碍诊断及管理中的作用与局限性。

方法

在5年期间,我们中心诊治了14例无感染背景的病理性迁移障碍胎儿。所有胎儿均接受了超声检查;其中9例还接受了磁共振成像检查。将超声和磁共振成像数据与神经病理学数据进行比较。

结果

超声检查在1/14例中诊断出脑回障碍;其余病例发现其他脑异常提示神经元紊乱。脑磁共振成像在9例中的8例提示脑回异常。

结论

超声检查的性能正在提高。磁共振成像似乎是诊断胎儿迁移障碍的一种有前景的方法,其结果优于超声检查。在脑超声检查结果异常或有家族临床病史的情况下可能会推荐使用。然而,磁共振成像的解读可能很棘手,且诊断结果在孕期较晚出现。

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