Amiel C, Chau C, Millet V, Agher J P, Gamerre M
Maternité Belle de Mai, Marseille.
J Gynecol Obstet Biol Reprod (Paris). 1993;22(3):284-8.
We report two cases of fetal supraventricular tachycardia with hydrops fetalis. The transplacental therapy with digoxin, sotalol and amiodarone, using combination of both of this drugs, has given in one case a partial conversion, total in the second case. Ultrasounds allow diagnosis of SVT, evaluate the gravity when it is associated with fetal hydrops secondary to a congestive heart failure, research a cause and follow the evolution during the treatment. The treatment must begin when diagnosis of SVT is done, by digoxin; other drugs as sotalol, amiodarone or flecainide acetate are described and also direct fetal therapy by intramuscular or into the umbilical vein injections.
我们报告了两例胎儿室上性心动过速合并胎儿水肿的病例。采用地高辛、索他洛尔和胺碘酮经胎盘治疗，两种药物联合使用，其中一例部分转复，另一例完全转复。超声检查可诊断室上性心动过速，评估其与充血性心力衰竭继发的胎儿水肿相关时的严重程度，查找病因并在治疗期间跟踪病情进展。一旦诊断为室上性心动过速，就必须开始治疗，首选地高辛；还介绍了其他药物，如索他洛尔、胺碘酮或醋酸氟卡尼，以及通过肌肉注射或脐静脉注射进行的直接胎儿治疗。
