Bayat Mohammad, Delbari Ali, Almaseyeh Mohammad Ali, Sadeghi Yousef, Bayat Maryam, Reziae Fatemesadat
Cell and Molecular Biology Research Center, Medical School, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Photomed Laser Surg. 2005 Dec;23(6):556-60. doi: 10.1089/pho.2005.23.556.
This study sought to investigate whether or not low-level laser therapy (LLLT) with a helium-neon laser increased biomechanical parameters of transected medial collateral ligament (MCL) in rats.
It has been reported that LLLT can enhance tendon healing.
Thirty rats received surgical transection to their right MCL, and five were assigned as the control group. After surgery, the rats were divided into three groups: group 1 (n = 10) received LLLT with 0.01 J/cm(2) energy density per day, group 2 (n = 10) received LLLT with 1.2 J/cm(2) energy density per day, and group 3 (sham = exposed group; n = 10) received daily placebo laser with shut-down laser equipment, while the control group received neither surgery nor LLLT. Biomechanical tests were performed at 12 and 21 days after surgery. The data were analyzed by one-way analysis of variance.
The ultimate tensile strength (UTS) of group 2 on day 12 was significantly higher than that of groups 1 and 3. Furthermore, the UTS and energy absorption of the control (uninjured) group were significantly higher than those of the other groups.
LLLT with a helium-neon laser is effective for the early improvement of the ultimate tensile strength of medial collateral ligament injuries.
本研究旨在调查氦氖激光低强度激光疗法（LLLT）是否能提高大鼠横断内侧副韧带（MCL）的生物力学参数。
据报道，低强度激光疗法可促进肌腱愈合。
30只大鼠右侧MCL接受手术横断，5只作为对照组。术后，大鼠被分为三组：第1组（n = 10）每天接受能量密度为0.01 J/cm²的低强度激光疗法，第2组（n = 10）每天接受能量密度为1.2 J/cm²的低强度激光疗法，第3组（假手术=暴露组；n = 10）每天接受关闭激光设备的安慰剂激光，而对照组既不接受手术也不接受低强度激光疗法。术后12天和21天进行生物力学测试。数据采用单因素方差分析。
第2组术后12天的极限拉伸强度（UTS）显著高于第1组和第3组。此外，对照组（未受伤）的UTS和能量吸收显著高于其他组。
氦氖激光低强度激光疗法对内侧副韧带损伤极限拉伸强度的早期改善有效。
