Pace S, Lotti G, Stentella P, Franceschini P, Mastrone M, Di Fonso G, Labi F L, Frega A, Di Renzi F, Grassi A
II Clinica Ostetrica e Ginecologica, Università degli Studi di Roma La Sapienza.
Minerva Ginecol. 1992 Jun;44(6):283-9.
The aim of this study was to assess the clinical efficiency of colposcopic findings as diagnostic tests for intraepithelial lesion using the analysis of colpo-cyto-histological correlations. The results of 3340 colposcopic tests performed in the Colposcopy Unit of the Second Clinic of Obstetrics and Gynecology between March 1990 and May 1991 were analysed, taking into account 326 (9.7%) cases of Abnormal Transformation Zone (ANTZ). The colpo-histological correlation in ANTZ 1 cases (52 cases of white epithelium, 92 standard mosaic, 42 standard dotted and 61 mixed cases) was 65.2% (52.3%) for HPV; 12.9% for CIN). The colpo-histological correlation in ANTZ 2 cases (30 cases of thickened white epithelium, 5 irregular mosaic, 4 irregular dotted, 2 atypical vessels, 4 thickened gland outlets and 6 mixed cases) was 70.5% (43.3% for HPV; 27.2% for CIN an and Ca). In this retrospective study colposcopy showed a diagnostic accuracy of 64.6% in the cases examined and played a decisive role in the diagnosis of intraepithelial lesions of the uterine cervix.
本研究旨在通过分析阴道镜-细胞学-组织学相关性,评估阴道镜检查结果作为上皮内病变诊断试验的临床效率。分析了1990年3月至1991年5月在第二妇产科诊所阴道镜室进行的3340例阴道镜检查结果,其中考虑了326例(9.7%)异常转化区(ANTZ)病例。ANTZ 1病例(52例白色上皮、92例标准镶嵌、42例标准点状及61例混合病例)的阴道镜-组织学相关性中,HPV为65.2%(52.3%),CIN为12.9%。ANTZ 2病例(30例增厚白色上皮、5例不规则镶嵌、4例不规则点状、2例非典型血管、4例增厚腺管开口及6例混合病例)的阴道镜-组织学相关性中,HPV为70.5%(43.3%),CIN及Ca为27.2%。在这项回顾性研究中,阴道镜检查在所检查病例中的诊断准确率为64.6%,在子宫颈上皮内病变的诊断中起决定性作用。