Caglar H, Creatsas G, Garcia-Bhandari T, Rodgers B, Wieckowska W, Hreshchyshyn M M
Diagn Gynecol Obstet. 1982 Winter;4(4):281-4.
White epithelium, mosaicism, punctation, and atypical vessels are internationally used colposcopic terms describing an atypical transformation zone. Other morphologic findings are surface contour, clarity of demarcation, and tone of whiteness with or without atypical vessels. In the State University of New York at Buffalo affiliated hospitals, 665 cervical and vaginal atypical colposcopic patterns of 552 patients were matched with their histologic findings. Mosaicism, punctation, and white epithelium correlated with the histologic diagnosis of vaginal intraepithelial neoplasia and cervical intraepithelial neoplasia in 43%, 55%, and 42% of the cases, respectively. When white epithelium accompanied the mosaicism or punctation, the incidence of histologically confirmed vaginal and cervical intraepithelial neoplasia raised to 66% and 68%, respectively. In patients with prenatal DES exposure, mosaicism rarely (17%) correlated with the histologic findings of vaginal and cervical intraepithelial neoplasia. Overall, there was a great variability in the correlation depending on the specific colposcopic abnormalities.
白色上皮、镶嵌征、点状征及非典型血管是国际上用于描述非典型转化区的阴道镜术语。其他形态学表现包括表面轮廓、边界清晰度以及有无非典型血管时白色的色泽。在纽约州立大学布法罗分校附属医院，对552例患者的665种宫颈和阴道非典型阴道镜图像模式与组织学检查结果进行了匹配。镶嵌征、点状征和白色上皮分别在43%、55%和42%的病例中与阴道上皮内瘤变和宫颈上皮内瘤变的组织学诊断相关。当白色上皮伴有镶嵌征或点状征时，经组织学证实的阴道和宫颈上皮内瘤变的发生率分别升至66%和68%。在产前暴露于己烯雌酚的患者中，镶嵌征很少（17%）与阴道和宫颈上皮内瘤变的组织学表现相关。总体而言，根据具体的阴道镜异常情况，相关性存在很大差异。
