Béres J, Tauszik T, Horányi M, Pazonyi I, Szelényi J, Hollán Z, Flatz G
Johan Béla Országos Közegészségügyi Intézet, Budapest.
Orv Hetil. 1992 Jul 26;133(30):1869-73.
In 1984 a late malaria endemic area, called Bodrogköz was studied. This was a reexamination of the population genetic work performed by Walter, Nemeskéri. In six villages of Bodrogköz 328 persons were tested for AB0, Rh blood groups, haptoglobins, haemoglobin concentration, haematocrit, erythrocyte amount, the MCV, the MCH and the G-6-PD were analyzed. The quantitative determination of HbF and HbA2, red cell osmotic resistance and thalassemia were measured as well. Thalassemia heterozygote carriers and an increased level of HbF were revealed. The frequency of G-6-PD deficiency was 0.39%. In Bodrogköz the frequencies of AB0, Rh and haptoglobin types were similar in the present and all previous studies. The background of this similarity might be the genetic similarity between two following generations. On the basis of these facts, the Hb0 Arab and partially DNA work we suggested an alternative hypothesis that these mutant genes got into Bodrogköz by the rather later migration than with ancient Hungarian people during the period of conquest of Hungary.
1984年，对一个名为博德罗格科兹的疟疾流行晚期地区进行了研究。这是对沃尔特和内梅斯凯里所做的群体遗传学研究工作的重新审视。在博德罗格科兹的6个村庄，对328人进行了AB0、Rh血型、触珠蛋白、血红蛋白浓度、血细胞比容、红细胞数量、平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）和葡萄糖-6-磷酸脱氢酶（G-6-PD）的检测分析。还测定了HbF和HbA2的定量、红细胞渗透抵抗力和地中海贫血情况。发现了地中海贫血杂合子携带者以及HbF水平升高的情况。G-6-PD缺乏症的发生率为0.39%。在博德罗格科兹，AB0、Rh和触珠蛋白类型的频率在本次研究和以往所有研究中都相似。这种相似性的背景可能是两代人之间的遗传相似性。基于这些事实，结合我们对Hb0阿拉伯人和部分DNA的研究工作，我们提出了另一种假设，即这些突变基因进入博德罗格科兹的时间，要比古代匈牙利人在征服匈牙利时期的迁移时间晚得多。
