Mseddi M, Hadj Taieb H, Abdelmaksoud W, Khemakhem M, Turki H, Masmoudi A, Zahaf A
Service de Dermatologie CHU H. Chaker, Sfax, Tunisie.
Rev Med Liege. 2005 Oct;60(10):772-4.
Bleomycin is an antibiotic with antineoplastic pro prieties. It is used in the traitement of many syndromes. The cutaneous toxicity of bleomycin includes many alteration. We report a case of flagellate erythema following the administration of bleomycin in a 57-year-old women with Kaposi sarcoma. She developped linear lesions 6 days after the first dose of bleomycin. Flagellate erythema is a specific reaction to bleomycin therapy wich occurs in susceptible individuals independently of dose, route of administration and type of malignant disease treated. Its occurs in 10 to 35% of the treated patients.