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[激光与发光二极管照射对伤口愈合及伤口渗出液白细胞功能活性影响的比较研究]

[A comparative study of the effects of laser and light-emitting diode irradiation on the wound healing and functional activity of wound exudate leukocytes].

作者信息

Klebanov G I, Shuraeva N Iu, Chichuk T V, Osipov A N, Rudenko T G, Shekhter A B, Vladimirov Iu A

出版信息

Biofizika. 2005 Nov-Dec;50(6):1137-44.

Abstract

The effects of coherent He-Ne laser and non-coherent light-emitting diode radiation on rat skin wound healing and functional activity of wound excudate leukocytes were compared. A comparative pathomorphological analysis showed that the He-Ne laser and light-emitting diode irradiation stimulated the transition of the inflammatory phase of the wound healing into the reparative (proliferative) and scarring phases sequentially. It was also detected that the functional activity of leucocytes changed in a dose-dependent manner. The leukocyte activity was found to be similar in the groups with laser and light-emitting diode irradiation. Thus, we can conclude that coherent laser and non-coherent light-emitting diode radiation have very close effects on wound healing and activity of wound exudate leukocytes, and coherence is not required for this activity.

摘要

比较了相干氦氖激光和非相干发光二极管辐射对大鼠皮肤伤口愈合及伤口渗出液白细胞功能活性的影响。对比病理形态学分析表明,氦氖激光和发光二极管照射依次刺激伤口愈合的炎症期向修复(增殖)期和瘢痕形成期转变。还检测到白细胞的功能活性呈剂量依赖性变化。发现激光照射组和发光二极管照射组的白细胞活性相似。因此,我们可以得出结论,相干激光和非相干发光二极管辐射对伤口愈合及伤口渗出液白细胞活性具有非常相似的作用,且这种作用不需要相干性。

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