Lee Bo-Eun, Ha Eun-Hee, Park Hye-sook, Kim Ho, Lee Hyun-Jung, Lee Yeon-Kyoung, Lee Seung-Joo, Hong Yun-Chul
Korean Centers for Disease Control.
J Prev Med Public Health. 2005 Nov;38(4):465-72.
The aim of this study was to assess the effect of air pollution on the daily respiratory symptoms of elementary school children in Seoul.
Using the panel study design, we collected diary data for the children's respiratory symptoms during the 1st day approximately 15th day of April, July, October and December in 2003 among the 2nd and 3rd grade elementary school students. We merged the respiratory symptom data with the ambient air pollution data that was monitored by Ministry of Environment. Using a generalized estimate equation, we evaluated the relationship between the daily symptoms of the subjects and the exposure to air pollution after controlling for various potential confounders.
The nitrogen dioxide (NO2) exposure of the current day significantly increased the upper respiratory symptoms (adjusted odds ratio=1.12, 95% CI=1.01-1.24) and the lower respiratory symptoms (adjusted odds ratio=1.18, 95% CI=1.06-1.31) in the elementary school children. The sulfur dioxide (SO2) and carbon monoxide (CO) exposure in the current day was associated with the lower respiratory symptoms (adjusted odds ratio=1.12, 95% CI=1.01-1.25 for SO2; adjusted odds ratio=1.16, 95% CI=1.02-1.32 for CO).
We found that exposure to air pollution affects the daily respiratory symptoms in children. This study suggests that the effect on children's health? due to the short term changes in air pollution levels needs to be considered as an important public health problem.
本研究旨在评估空气污染对首尔小学生日常呼吸道症状的影响。
采用面板研究设计,我们收集了2003年4月、7月、10月和12月的第1天至约第15天期间二年级和三年级小学生呼吸道症状的日记数据。我们将呼吸道症状数据与环境部监测的环境空气污染数据合并。使用广义估计方程,在控制各种潜在混杂因素后,我们评估了受试者的日常症状与空气污染暴露之间的关系。
当日的二氧化氮(NO₂)暴露显著增加了小学生的上呼吸道症状(调整后的优势比=1.12,95%置信区间=1.01-1.24)和下呼吸道症状(调整后的优势比=1.18,95%置信区间=1.06-1.31)。当日的二氧化硫(SO₂)和一氧化碳(CO)暴露与下呼吸道症状相关(SO₂的调整后的优势比=1.12,95%置信区间=1.01-1.25;CO的调整后的优势比=1.16,95%置信区间=1.02-1.32)。
我们发现空气污染暴露会影响儿童的日常呼吸道症状。本研究表明,空气污染水平的短期变化对儿童健康的影响需要被视为一个重要的公共卫生问题。