深部脑刺激用于缓解中风后神经性疼痛。
Deep brain stimulation for the alleviation of post-stroke neuropathic pain.
作者信息
Owen Sarah L F, Green Alexander L, Stein John F, Aziz Tipu Z
机构信息
University Laboratory of Physiology, University of Oxford, Oxford, UK Department of Neurological Surgery, Radcliffe Infirmary, Oxford, UK.
出版信息
Pain. 2006 Jan;120(1-2):202-206. doi: 10.1016/j.pain.2005.09.035. Epub 2005 Dec 15.
Our aim was to asses the efficacy of deep brain stimulation in post-stroke neuropathic pain. Since 2000, 15 patients with post-stroke intractable neuropathic pain were treated with deep brain stimulation of the periventricular gray area (PVG), sensory thalamus (Ventroposterolateral nucleus-VPL) or both. Pain was assessed using both a visual analogue scale and the McGill's pain questionnaire. VAS scores show a mean improvement of 48.8% (SD 8.6%). However, there is a wide variation between patients. This study demonstrates that it is an effective treatment in 70% of such patients.
我们的目的是评估深部脑刺激治疗中风后神经性疼痛的疗效。自2000年以来，15名中风后顽固性神经性疼痛患者接受了脑室周围灰质区（PVG）、感觉丘脑（腹后外侧核-VPL）或两者的深部脑刺激治疗。使用视觉模拟量表和麦吉尔疼痛问卷对疼痛进行评估。视觉模拟量表评分显示平均改善了48.8%（标准差8.6%）。然而，患者之间存在很大差异。这项研究表明，在70%的此类患者中，这是一种有效的治疗方法。
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