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一大群前列腺癌男性患者中补充和替代医学的总体及特定使用情况

Total and specific complementary and alternative medicine use in a large cohort of men with prostate cancer.

作者信息

Chan J M, Elkin E P, Silva S J, Broering J M, Latini D M, Carroll P R

机构信息

Department of Urology, University of California-San Francisco, California 94143-1695, USA.

出版信息

Urology. 2005 Dec;66(6):1223-8. doi: 10.1016/j.urology.2005.06.003.

DOI:10.1016/j.urology.2005.06.003
PMID:16360447
Abstract

OBJECTIVES

To assess specific complementary and alternative medicine (CAM) use in the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), a large, community-based national registry of men with prostate cancer.

METHODS

We examined more than 50 types of CAM use in a large, national, community-based registry of men with prostate cancer (CaPSURE). Participants completed biannual surveys within 2 years of diagnosis and treatment. We analyzed associations of CAM use with sociodemographic and clinical features, using chi-square tests and multivariate logistic regression.

RESULTS

One third of 2582 respondents reported using CAM. Common practices included vitamin and mineral supplements (26%), herbs (16%), antioxidants (13%), and CAM for prostate health (12%; eg, saw palmetto, selenium, vitamin E, lycopene). In multivariate analyses, users were more likely to have other comorbid conditions, worse cancer grade at diagnosis, higher incomes, more education, and to live in the West.

CONCLUSIONS

Complementary and alternative medicine use was associated with sociodemographic and clinical characteristics in this large sample of men with prostate cancer. These results should be considered by health care professionals counseling men with prostate cancer regarding diet and secondary prevention.

摘要

目的

在前列腺癌战略泌尿学研究项目(CaPSURE)中评估特定补充和替代医学(CAM)的使用情况,CaPSURE是一个基于社区的大型全国性前列腺癌男性登记处。

方法

我们在一个基于社区的大型全国性前列腺癌男性登记处(CaPSURE)中研究了50多种CAM的使用情况。参与者在诊断和治疗后的2年内完成了半年一次的调查。我们使用卡方检验和多变量逻辑回归分析了CAM使用与社会人口统计学和临床特征之间的关联。

结果

2582名受访者中有三分之一报告使用过CAM。常见做法包括维生素和矿物质补充剂(26%)、草药(16%)、抗氧化剂(13%)以及用于前列腺健康的CAM(12%;如锯棕榈、硒、维生素E、番茄红素)。在多变量分析中,使用者更有可能患有其他合并症、诊断时癌症分级更差、收入更高、受教育程度更高且居住在西部。

结论

在这个大型前列腺癌男性样本中,补充和替代医学的使用与社会人口统计学和临床特征相关。医疗保健专业人员在为前列腺癌男性提供饮食和二级预防咨询时应考虑这些结果。

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