Lee Daniel J, Lustig Lawrence, Sampson Margaret, Chinnici Jill, Niparko John K
Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Otolaryngol Head Neck Surg. 2005 Dec;133(6):900-5. doi: 10.1016/j.otohns.2005.08.013.
Human cytomegalovirus (CMV) is a commonly recognized viral cause of perinatal sensorineural hearing loss. CMV-infected infants are also at risk for developmental neurological deficits. This retrospective study assesses the impact of CMV-induced deafness on pediatric cochlear implant outcomes.
Thirteen patients from the Johns Hopkins pediatric cochlear implant database were identified with CMV-related deafness. A retrospective review of the medical records of the Johns Hopkins Hospital was performed.
The mean age at implantation was 5.6 years. Follow-up audiometric data ranged from 6 to 48 months postoperatively. Mean speech perception scores were 4.5 (out of 6) following implantation.
We have shown that cochlear implants can provide useful speech comprehension to patients with CMV-related deafness. Speech recognition scores were within the range established by our overall pediatric implant population.
This observation underscores the importance of a multidisciplinary rehabilitation program following implantation in these patients at risk for cognitive delay.
人巨细胞病毒（CMV）是围产期感音神经性听力损失常见的已知病毒病因。CMV感染的婴儿也有发生发育性神经功能缺损的风险。这项回顾性研究评估了CMV所致耳聋对儿童人工耳蜗植入效果的影响。
从约翰霍普金斯儿童人工耳蜗植入数据库中确定了13例患有CMV相关性耳聋的患者。对约翰霍普金斯医院的病历进行了回顾性分析。
植入时的平均年龄为5.6岁。术后听力测定随访数据为术后6至48个月。植入后平均言语感知评分为4.5（满分6分）。
我们已表明人工耳蜗可为CMV相关性耳聋患者提供有效的言语理解能力。言语识别分数在我们整个儿童植入人群所确定的范围内。
这一观察结果强调了对这些有认知延迟风险的患者在植入后开展多学科康复计划的重要性。
