巨细胞病毒（CMV）相关性耳聋对小儿人工耳蜗植入效果的影响。

Effects of cytomegalovirus (CMV) related deafness on pediatric cochlear implant outcomes.

作者信息

Lee Daniel J, Lustig Lawrence, Sampson Margaret, Chinnici Jill, Niparko John K

机构信息

Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

出版信息

Otolaryngol Head Neck Surg. 2005 Dec;133(6):900-5. doi: 10.1016/j.otohns.2005.08.013.

DOI:10.1016/j.otohns.2005.08.013

PMID:16360511

Abstract

OBJECTIVE

Human cytomegalovirus (CMV) is a commonly recognized viral cause of perinatal sensorineural hearing loss. CMV-infected infants are also at risk for developmental neurological deficits. This retrospective study assesses the impact of CMV-induced deafness on pediatric cochlear implant outcomes.

STUDY DESIGN AND SETTING

Thirteen patients from the Johns Hopkins pediatric cochlear implant database were identified with CMV-related deafness. A retrospective review of the medical records of the Johns Hopkins Hospital was performed.

RESULTS

The mean age at implantation was 5.6 years. Follow-up audiometric data ranged from 6 to 48 months postoperatively. Mean speech perception scores were 4.5 (out of 6) following implantation.

CONCLUSION

We have shown that cochlear implants can provide useful speech comprehension to patients with CMV-related deafness. Speech recognition scores were within the range established by our overall pediatric implant population.

SIGNIFICANCE

This observation underscores the importance of a multidisciplinary rehabilitation program following implantation in these patients at risk for cognitive delay.

摘要