Suppr超能文献

软腭射频组织减容术及悬雍垂腭咽成形术治疗打鼾

Radiofrequency tissue volume reduction of the soft palate and UPPP in the treatment of snoring.

作者信息

Hofmann T, Schwantzer G, Reckenzaun E, Koch H, Wolf G

机构信息

Department of Otorhinolaryngology, University Hospital Graz, Auenbruggerplatz 26, 8036, Graz, Austria.

出版信息

Eur Arch Otorhinolaryngol. 2006 Feb;263(2):164-70. doi: 10.1007/s00405-005-0959-5. Epub 2005 Dec 16.

Abstract

The purpose of this study was to evaluate the efficiency of radiofrequency tissue volume reduction (RFTVR) and uvulopalatopharyngoplasty (UPPP) in the treatment of snoring in a prospective clinical trial of 79 patients consecutively undergoing surgery for snoring. Seventy-nine patients with primary snoring or mild OSAS (obstructive sleep apnea syndrome) were enrolled in this clinical trial (66 males and 13 females). According to the anatomical findings (the size of the tonsils and uvula), the patients underwent UPPP/TE of the RFTVR of the soft palate. Forty-seven patients had UPPP/TE (age 45.81+/-12.11 years; median AHI: 8; range 1-29). Thirty-two patients were treated with RFTVR of the soft palate (age 48.10+/-10.92; median AHI: 5.0; range 0-26). The average number of treatments was 2.2. All patients underwent preoperative polysomnography to exclude severe OSAS. Pre- and postoperative snoring scores were evaluated from the patients with bed partners. Postoperative follow-up data were collected at a median of 4 months after treatment; 85.1% of the UPPP group and 53.1% of the RFTVR group underwent postoperative polysomnography. Subjective snoring scores of all study participants were evaluated. Preoperatively, there was no statistically significant difference of subjective symptoms, age and BMI between the two groups. The snoring scores improved statistically significantly in both groups (P <0.001 in the UPPP group; P =0.001 in the RFTVR group). After UPPP/TE snoring improved in 37 patients (78.7%), and 29 (61.7%) thereof were free of bothersome snoring; no change was found in 9 patients (19.2%), and 1 (2.1%) worsened. In the RFTVR group, snoring improved in 15 (46.9%), and 9 (28.1%) thereof were free of bothersome snoring; no change was found in 13 patients (50%), and 1 worsened (3.1%). Preoperative AHI was statistically higher (P =0.016) and mean minimal oxygen saturation significantly lower (P =0.002) in the UPPP group. In the UPPP group AHI and HI showed statistically significant improvement postoperatively (P =0.025 and P =0.034, respectively). After RFTVR, no statistically significant change of AHI, HI or oxygen saturation was found. Besides limited mucosal erosions (15%) after RFTVR and foreign body sensations (<10%) after UPPP/TE, no side effects were observed. The success rate of RFTVR of the soft palate is lower compared to the more invasive technique of UPPP. Due to its minimally invasive character, RFTVR is suitable as first-step treatment for snoring, but patients should be counseled about possible success rates and different treatment options.

摘要

本研究的目的是在一项对79例连续接受打鼾手术的患者进行的前瞻性临床试验中,评估射频组织体积减小术(RFTVR)和悬雍垂腭咽成形术(UPPP)治疗打鼾的效果。79例原发性打鼾或轻度阻塞性睡眠呼吸暂停综合征(OSAS)患者纳入了该临床试验(66例男性和13例女性)。根据解剖学检查结果(扁桃体和悬雍垂的大小),患者接受软腭的UPPP/TE或RFTVR。47例患者接受UPPP/TE(年龄45.81±12.11岁;平均呼吸暂停低通气指数:8;范围1 - 29)。32例患者接受软腭RFTVR治疗(年龄48.10±10.92岁;平均呼吸暂停低通气指数:5.0;范围0 - 26)。平均治疗次数为2.2次。所有患者术前均接受多导睡眠图检查以排除重度OSAS。由有同床伴侣的患者评估术前和术后的打鼾评分。术后随访数据在治疗后中位时间4个月收集;UPPP组85.1%和RFTVR组53.1%的患者接受了术后多导睡眠图检查。对所有研究参与者的主观打鼾评分进行了评估。术前,两组间主观症状、年龄和体重指数无统计学显著差异。两组的打鼾评分均有统计学显著改善(UPPP组P <0.001;RFTVR组P =0.001)。UPPP/TE后,37例患者(78.7%)打鼾改善,其中29例(61.7%)无烦人的打鼾;9例(19.2%)无变化,1例(2.1%)病情恶化。在RFTVR组,15例(46.9%)打鼾改善,其中9例(28.1%)无烦人的打鼾;13例(50%)无变化,1例(3.1%)病情恶化。UPPP组术前平均呼吸暂停低通气指数统计学上更高(P =0.016),平均最低血氧饱和度显著更低(P =0.002)。在UPPP组,术后平均呼吸暂停低通气指数和呼吸紊乱指数有统计学显著改善(分别为P =0.025和P =0.034)。RFTVR后,平均呼吸暂停低通气指数、呼吸紊乱指数或血氧饱和度无统计学显著变化。除了RFTVR后有限的黏膜糜烂(15%)和UPPP/TE后的异物感(<10%)外,未观察到其他副作用。与侵入性更强的UPPP技术相比,软腭RFTVR的成功率较低。由于其微创性,RFTVR适合作为打鼾的第一步治疗方法,但应向患者告知可能的成功率和不同的治疗选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验