Wojcik E M, Naylor B
Department of Pathology, University of Michigan, Ann Arbor.
Acta Cytol. 1992 Jul-Aug;36(4):466-70.
Peritoneal washings obtained at laparotomy from women undergoing surgery for neoplasms of the genital tract may contain "collagen balls," consisting of tissue fragments composed of collagen covered with mesothelial cells. Collagen balls were found in 19 (4.5%) of 418 peritoneal washings and were more prevalent in specimens labeled pelvic washings (17 of 294, or 5.8%) than in those labeled peritoneal washings (2 of 124, or 1.6%). In 15 of the 19 cases in which we found collagen balls, at least one ovary was available for microscopic examination. In 14 of the 15 cases minute nodular papillary stromal projections covered with mesothelium were found on the surface of the ovaries. We conclude that collagen balls, a nonspecific entity, most probably originate on the surface of the ovaries. Their significance lies in their being mistaken for mucin-distended cells exfoliated from a neoplasm or from detached fragments of a papillary ovarian neoplasm.
在剖腹手术中，从接受生殖道肿瘤手术的女性身上获取的腹腔冲洗液可能含有“胶原球”，其由覆盖间皮细胞的胶原组织碎片构成。在418份腹腔冲洗液中，有19份（4.5%）发现了胶原球，且在标记为盆腔冲洗液的标本中更为常见（294份中有17份，即5.8%），而在标记为腹腔冲洗液的标本中较少见（124份中有2份，即1.6%）。在发现胶原球的19例病例中，有15例至少有一个卵巢可供显微镜检查。在这15例中的14例中，在卵巢表面发现了覆盖间皮的微小结节状乳头样间质突起。我们得出结论，胶原球作为一种非特异性实体，很可能起源于卵巢表面。其意义在于它们可能被误认为是从肿瘤或乳头状卵巢肿瘤脱落碎片中脱落的黏液膨胀细胞。
