Leino M, Carlson C, Kilkku O, Kumpulainen T, Kyrönpalo-Kauppinen S, Laaka V, Norio M, Valtola J
Department of Ophthalmology, University Hospital of Kuopio, Finland.
Acta Ophthalmol (Copenh). 1992 Jun;70(3):341-5. doi: 10.1111/j.1755-3768.1992.tb08575.x.
A multicentre, group comparative open study was carried out on 68 patients to compare the effects of 2% sodium cromoglycate eyedrops and an oral antihistamine, terfenadine, on acute symptoms of seasonal allergic conjunctivitis. The study was continued for one week after the onset of acute symptoms. Both medications were equally efficient in reducing symptoms during the first hour of observation. During the one-week follow-up both medications reduced symptoms to a low level, and both medications were equally effective for allergic symptoms, except that terfenadine was more effective in reducing the watering of eyes.
对68例患者进行了一项多中心、组间比较开放性研究,以比较2%色甘酸钠滴眼液和口服抗组胺药特非那定对季节性过敏性结膜炎急性症状的疗效。急性症状出现后研究持续了一周。在观察的第一个小时内,两种药物在减轻症状方面同样有效。在为期一周的随访中,两种药物都将症状减轻到了较低水平,且两种药物对过敏症状同样有效,只是特非那定在减少流泪方面更有效。