Nogueras Gimeno M A, Espuela Orgaz R, Abad Menor F, Martínez Pérez E, Pérez Arbej J A, Arnaiz Esteban F, Fernández Rosaenz J, Guinda Sevillano C
Servicio de Urología, Hospital del Insalud, Soria.
Actas Urol Esp. 1992 Apr;16(4):316-20.
The incidence and features of malignant primary multiple (MPM) neoplasias found in clinical urological patients have been analyzed so as to determine the actual magnitude of the problem and to obtain a better knowledge of this disease. For this reason, case histories of patients with MPMN, where at least one of the involved neoplasia was urological, were retrospectively studied. The study included a 9-year follow-up period and followed the Warren and Gates inclusion criteria. The number of MPMN patients was 23, representing an incidence of 6.1% among patients with urological neoplasias. Mean age at the time of discovery of the second tumour was 77.1 years. In the 15 patients with metachronic tumours, the time interval between the first and second tumours ranged between 1 to 25 years (average 5.4 years). The most frequently observed tumour association was bladder transitional carcinoma and prostate adenocarcinoma. The cause of death was always the second neoplasia.
对临床泌尿外科患者中发现的原发性恶性多发性肿瘤（MPM）的发病率和特征进行了分析，以确定该问题的实际严重程度，并更好地了解这种疾病。因此，对MPMN患者（其中至少有一种受累肿瘤为泌尿系统肿瘤）的病历进行了回顾性研究。该研究包括9年的随访期，并遵循沃伦和盖茨纳入标准。MPMN患者有23例，在泌尿系统肿瘤患者中的发病率为6.1%。发现第二个肿瘤时的平均年龄为77.1岁。在15例异时性肿瘤患者中，第一个和第二个肿瘤之间的时间间隔为1至25年（平均5.4年）。最常观察到的肿瘤关联是膀胱移行癌和前列腺腺癌。死亡原因总是第二个肿瘤。
