Leung Janice, Wang Nae-Yuh, Yeagle Jennifer D, Chinnici Jill, Bowditch Stephen, Francis Howard W, Niparko John K
Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Arch Otolaryngol Head Neck Surg. 2005 Dec;131(12):1049-54. doi: 10.1001/archotol.131.12.1049.
An aging American population carries a high prevalence of profound sensorineural hearing loss. We examined the performance of multichannel cochlear implant recipients in a large database of adult subjects.
Nonconcurrent prospective study of a national cohort with multivariate regression analysis of preoperative and postoperative performance variables in multichannel cochlear implant recipients. We applied models of prediction established in previous studies to the observed results.
Referral centers with active cochlear implant programs.
Adolescents and adults with profound hearing loss (N = 749; age range, 14-91 years).
Postoperative monosyllabic word recognition.
The population 65 years and older demonstrated a clinically insignificant 4.6%-smaller postoperative word score compared with the population younger than 65 years. When duration of deafness exceeded 25 years, elderly recipients demonstrated higher word scores than their younger counterparts. A more significant factor affecting outcomes is the ratio of duration of deafness to age at implantation.
Age at implantation carried relatively little predictive value for postoperative performance in subjects 65 years and older. Although a small decrement in mean speech recognition scores was evident, the clinical significance of this difference is questionable when all of the results observed in elderly patients are considered. A shorter percentage of life spent in severe-to-profound sensorineural hearing loss suggests a foundation of acoustic/auditory processing in the elderly cohort that may mitigate potential physiological effects associated with advanced age. This study confirms and extends previous observations that duration of profound deafness and residual speech recognition carry higher predictive value than the age at which an individual receives an implant.
美国老龄化人口中重度感音神经性听力损失的患病率很高。我们在一个大型成年受试者数据库中研究了多通道人工耳蜗植入受者的表现。
对全国队列进行非同期前瞻性研究,对多通道人工耳蜗植入受者术前和术后的表现变量进行多变量回归分析。我们将先前研究中建立的预测模型应用于观察结果。
开展人工耳蜗植入项目的转诊中心。
患有重度听力损失的青少年和成年人(N = 749;年龄范围为14 - 91岁)。
术后单音节词识别率。
65岁及以上人群术后单词得分比65岁以下人群低4.6%,但在临床上无显著意义。当耳聋持续时间超过25年时,老年受者的单词得分高于年轻受者。影响结果更重要酌因素是耳聋持续时间与植入时年龄的比值。
对于65岁及以上的受试者,植入时的年龄对术后表现的预测价值相对较小。虽然平均言语识别得分有明显小幅下降,但考虑到老年患者观察到的所有结果后,这种差异的临床意义值得怀疑。在重度至极重度感音神经性听力损失中度过的生命时间较短,这表明老年人群体存在声学/听觉处理基础,可能减轻与高龄相关的潜在生理影响。本研究证实并扩展了先前的观察结果,即重度耳聋持续时间和残余言语识别能力比个体接受植入的年龄具有更高的预测价值。