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[解剖结构正常的耳蜗的个体化植入体选择:人工耳蜗植入手术迈向个性化医疗之路]

[Individualized implant selection for an anatomically normal cochlea : Cochlear implant surgery on the way to personalized medicine].

作者信息

Salcher Rolf B, Di Micco Riccardo, Timm Max E

机构信息

Hals-Nasen-Ohrenklinik & DHZ, Medizinische Hochschule Hannover, Hannover, Deutschland.

Hearing4all Exzellenzcluster, Hannover, Deutschland.

出版信息

HNO. 2025 Apr 11. doi: 10.1007/s00106-025-01625-0.

DOI:10.1007/s00106-025-01625-0
PMID:40214749
Abstract

BACKGROUND

Due to the anatomical variety of the human cochlea and the many factors that may determine the choice of the cochlear array, there is no one-size-fits-all method for determining the right implant. The cochlear size, preoperative residual hearing, anatomical variants, operative technique, and cause of deafness must be taken into consideration when making this decision.

OBJECTIVE

This work aims to spread awareness of precision surgery and provide an overview.

MATERIALS AND TECHNIQUES

Factors that contribute to individualization are explained, and future advances are outlined.

RESULTS

The optimum treatment, if possible, is electroacoustic stimulation. Cochlear coverage of approximately 80% should be the goal when using electrical stimulation alone.

CONCLUSION

In order to maximize rehabilitation results, recent developments in cochlear implantation mark a paradigm shift away from standardized treatments and toward individualized therapy.

摘要

背景

由于人类耳蜗的解剖结构多样,以及许多可能决定耳蜗植入阵列选择的因素,不存在一种适用于所有情况的确定合适植入物的方法。在做出这一决定时,必须考虑耳蜗大小、术前残余听力、解剖变异、手术技术和耳聋原因。

目的

这项工作旨在提高对精准手术的认识并提供概述。

材料与技术

解释了有助于个体化的因素,并概述了未来的进展。

结果

如果可能,最佳治疗方法是电声刺激。单独使用电刺激时,耳蜗覆盖率约80%应作为目标。

结论

为了使康复效果最大化,人工耳蜗植入的最新进展标志着从标准化治疗向个体化治疗的范式转变。

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1
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HNO. 2025 Apr 11. doi: 10.1007/s00106-025-01625-0.
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本文引用的文献

1
Estimation of outer-wall length in optimizing cochlear implantation in malformed inner ears.估算畸形内耳耳蜗植入中外壁长度。
Sci Rep. 2024 Nov 9;14(1):27308. doi: 10.1038/s41598-024-77991-6.
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Outcomes following cochlear implantation with eluting electrodes: A systematic review.使用洗脱电极进行人工耳蜗植入后的结果:一项系统评价。
Laryngoscope Investig Otolaryngol. 2024 Jun 7;9(3):e1263. doi: 10.1002/lio2.1263. eCollection 2024 Jun.
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[Comprehensive literature review on the application of the otological-surgical planning software OTOPLAN® for cochlear implantation. German version].
[关于耳科手术规划软件OTOPLAN®在人工耳蜗植入中应用的综合文献综述。德文版]
HNO. 2024 Oct;72(10):687-701. doi: 10.1007/s00106-024-01461-8. Epub 2024 Apr 8.
4
Evaluation of an impedance-based method to monitor the insertion of the electrode array during cochlear implantation.基于阻抗的方法评估在人工耳蜗植入过程中监测电极阵列插入的效果。
Eur Arch Otorhinolaryngol. 2024 Aug;281(8):4121-4131. doi: 10.1007/s00405-024-08584-2. Epub 2024 Apr 2.
5
Correlation of Scalar Cochlear Volume and Hearing Preservation in Cochlear Implant Recipients with Residual Hearing.残余听力的人工耳蜗植入患者中纯音耳蜗体积与听力保护的相关性
Otol Neurotol. 2024 Mar 1;45(3):256-265. doi: 10.1097/MAO.0000000000004122. Epub 2024 Jan 24.
6
Cochlear coverage with lateral wall cochlear implant electrode arrays affects post-operative speech recognition.外侧壁耳蜗植入电极阵列的耳蜗覆盖范围影响术后言语识别。
PLoS One. 2023 Jul 12;18(7):e0287450. doi: 10.1371/journal.pone.0287450. eCollection 2023.
7
Virtual cochlear implantation for personalized rehabilitation of profound hearing loss.虚拟现实耳蜗植入术用于深度听力损失的个性化康复。
Hear Res. 2023 Mar 1;429:108687. doi: 10.1016/j.heares.2022.108687. Epub 2022 Dec 27.
8
MicroRNA Profiling in the Perilymph of Cochlear Implant Patients: Identifying Markers that Correlate to Audiological Outcomes.耳蜗植入患者外淋巴液中的 microRNA 谱分析:确定与听力学结果相关的标志物。
J Am Acad Audiol. 2021 Nov;32(10):627-635. doi: 10.1055/s-0041-1742234. Epub 2022 May 24.
9
Proteome profile of patients with excellent and poor speech intelligibility after cochlear implantation: Can perilymph proteins predict performance?人工耳蜗植入后言语可懂度良好和不佳患者的蛋白质组图谱:外淋巴液蛋白能否预测性能?
PLoS One. 2022 Mar 3;17(3):e0263765. doi: 10.1371/journal.pone.0263765. eCollection 2022.
10
Implications of Phase Changes in Extracochlear Electrocochleographic Recordings During Cochlear Implantation.耳蜗植入过程中外周电 Cochleogram 相位变化的意义。
Otol Neurotol. 2022 Feb 1;43(2):e181-e190. doi: 10.1097/MAO.0000000000003414.