Participation of manganese ions complexed with tRNA in the interaction with amino acids and dipeptides.
作者信息
Weiner L M, Backer J M, Rezvukhin A I
出版信息
Biochim Biophys Acta. 1975 Mar 21;383(3):316-24. doi: 10.1016/0005-2787(75)90060-x.
PMID:163657
Abstract
Carboxyl groups of glycine, beta-alanine, gamma-aminobutyric acid and diglycine interact with Mn2+ coordinated by tRNA, as revealed by 1H and 13C NMR studies. The amino groups of these compounds interact with tRNA phosphate groups. The distances between the coordinated Mn2+ and carboxyl groups and the alpha-protons of glycine were determined. The role of Mn2+ and Mg2+ complexed with nucleic acids in the formation of specific complexes between proteins and nucleic acids is discussed.
摘要
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