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大动脉炎患者主动脉弓修复的手术结果。

Surgical outcome of aortic arch repair for patients with Takayasu arteritis.

作者信息

Matsuura Kaoru, Ogino Hitoshi, Matsuda Hitoshi, Minatoya Kenji, Sasaki Hiroaki, Yagihara Toshikatsu, Kitamura Soichiro

机构信息

National Cardiovascular Center, Suita City, Osaka, Japan.

出版信息

Ann Thorac Surg. 2006 Jan;81(1):178-82. doi: 10.1016/j.athoracsur.2005.06.043.

Abstract

BACKGROUND

Takayasu arteritis can cause segmental dilatation or stenosis of the aorta and its major branches, and surgical treatment of it is still difficult. Our objective was to review late results of aortic arch repair for patients with Takayasu arteritis.

METHODS

Between 1987 and 2003, 21 patients underwent aortic arch repair under circulatory arrest. Diagnosis was performed by pathologic study of specimens for all patients. Total aortic arch repair was performed in 12 patients with separated branched grafts and in 2 patients with the island technique. Selective cerebral perfusion was used in 12 patients and retrograde cerebral perfusion in 2 patients in this type of surgery. Hemiarch replacement using retrograde cerebral perfusion was performed in 7 patients. Craniocervical vascular stenosis was found in 7 patients and aneurysm in 5 patients. The elephant trunk technique was used in 10 patients. The follow-up period was 6.2 +/- 4.2 years.

RESULTS

There was one hospital death due to renal failure, and two late deaths, both of which were sudden. Late in follow-up, a patient who had undergone hemiarch replacement 12 years previously required total aortic arch repair for dilatation of the distal arch. Three patients required thoracoabdominal aortic repair and one patient descending aortic repair for residual aortic dilatation late in follow-up. Postoperative spinal infarction occurred in one patient who underwent hemiarch replacement.

CONCLUSIONS

Surgical and late outcomes of aortic arch repair under circulatory arrest appear favorable, though late dilatation of the residual aorta is a matter of concern.

摘要

背景

大动脉炎可导致主动脉及其主要分支的节段性扩张或狭窄,其外科治疗仍具有挑战性。我们的目的是回顾大动脉炎患者主动脉弓修复的远期结果。

方法

1987年至2003年间,21例患者在循环阻断下接受了主动脉弓修复。所有患者均通过标本病理研究进行诊断。12例患者采用分支移植物分离技术进行全主动脉弓修复,2例患者采用岛状技术。此类手术中,12例患者采用选择性脑灌注,2例患者采用逆行脑灌注。7例患者采用逆行脑灌注进行半弓置换。7例患者发现颅颈血管狭窄,5例患者发现动脉瘤。10例患者采用象鼻技术。随访时间为6.2±4.2年。

结果

1例患者因肾衰竭在医院死亡,2例患者出现晚期死亡,均为猝死。随访后期,1例12年前接受半弓置换的患者因远端弓扩张需要进行全主动脉弓修复。3例患者因随访后期残余主动脉扩张需要进行胸腹主动脉修复,1例患者需要进行降主动脉修复。1例接受半弓置换的患者术后发生脊髓梗死。

结论

循环阻断下主动脉弓修复的手术及远期结果似乎良好,尽管残余主动脉的晚期扩张是一个值得关注的问题。

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