Linde K, Weidenhammer W, Streng A, Hoppe A, Melchart D
Department of Internal Medicine II, Technische Universität München, Kaiserstrasse 9, 80801 Munich, Germany.
Rheumatology (Oxford). 2006 Feb;45(2):222-7. doi: 10.1093/rheumatology/kei252. Epub 2005 Dec 20.
To investigate characteristics and outcomes of patients undergoing acupuncture treatment for osteoarthritic pain under conditions of routine care in the framework of statutory health insurance in Germany.
Patients with chronic pain due to osteoarthritis (ICD-10 diagnoses M15 to M19) treated with acupuncture as the leading form of therapy were included in an observational study. Detailed questionnaires including instruments to measure pain intensity (numerical rating scales from 0 to 10), disability (Pain Disability Index) and quality of life (SF-36) were filled in before treatment, after treatment and at 6 months. Patients suffering from osteoarthritis of the knee and hip also filled in the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index questionnaire.
A total of 736 patients were included in the main analysis. Seventy (10%) patients and 278 (38%) patients, respectively, suffered exclusively from primary osteoarthritis of the hip or knee, 239 (33%) from another type of osteoarthritis and 149 (20%) had more than one affected joint. On average, patients received 8.7 +/- 3.1 acupuncture treatments. Statistically significant and clinically relevant improvements were seen in all subgroups both after treatment and at 6 months in all major outcome measures. In patients with osteoarthritis of the hip, the WOMAC sum score was 47.9 +/- 20.7 at baseline, 34.8 +/- 20.0 after treatment and 33.1 +/- 22.2 at 6 months. The respective values in patients with osteoarthritis of the knee were 51.7 +/- 20.9, 34.1 +/- 23.3 and 34.6 +/- 25.1.
In this study, patients with chronic pain due to osteoarthritis reported clinically relevant improvements after acupuncture treatment. Due to the uncontrolled design and the high proportion of patients lost to follow-up, the study findings must be interpreted cautiously.
在德国法定医疗保险框架下的常规护理条件下,研究接受针刺治疗骨关节炎疼痛患者的特征及治疗结果。
以针刺作为主要治疗方式治疗慢性骨关节炎疼痛(国际疾病分类第十版诊断编码为M15至M19)的患者纳入一项观察性研究。在治疗前、治疗后及6个月时填写详细问卷,包括测量疼痛强度(0至10数字评分量表)、残疾程度(疼痛残疾指数)和生活质量(SF - 36)的工具。患有膝和髋骨关节炎的患者还填写了西安大略和麦克马斯特大学(WOMAC)骨关节炎指数问卷。
共有736例患者纳入主要分析。分别有70例(10%)患者和278例(38%)患者仅患有原发性髋或膝骨关节炎,239例(33%)患有其他类型骨关节炎,149例(20%)有一个以上关节受累。患者平均接受8.7±3.1次针刺治疗。在所有主要结局指标中,各亚组在治疗后及6个月时均出现了具有统计学意义且临床相关的改善。髋骨关节炎患者的WOMAC总分在基线时为47.9±20.7,治疗后为34.8±20.0,6个月时为33.1±22.2。膝骨关节炎患者的相应值分别为51.7±20.9、34.1±23.3和34.6±25.1。
在本研究中,骨关节炎慢性疼痛患者在针刺治疗后报告了临床相关改善。由于研究设计未设对照且失访患者比例高,研究结果必须谨慎解读。