O'Riordain D S, Buckley D J, O'Donnell J A
Department of Surgery, University College, Cork, Ireland.
Am J Surg. 1992 Aug;164(2):129-31. doi: 10.1016/s0002-9610(05)80370-8.
Seventy-one consecutive above-knee polytetrafluoroethylene (PTFE) femoropopliteal arterial bypasses performed between 1981 and 1989 for critical ischemia were followed prospectively to determine graft patency and limb salvage. Cumulative graft patency and limb salvage rates were calculated by life table analysis. Graft patency was 80%, 68%, 55%, 39%, and 39%, and limb salvage 97%, 87%, 84%, 77%, and 77% at 1, 2, 3, 4, and 5 years, respectively. Twenty-nine grafts have occluded with re-emergence of critical ischemia in 14, treated by 5 amputations and 9 reconstructions using autogenous saphenous vein (ASV) in 6 and PTFE in 3. These favorable results are not as good in terms of primary patency as those reported with ASV, but good limb salvage, good early patency, ease of use, and preservation of the saphenous vein for use later have encouraged us toward primary use of PTFE in selected patients. This experience strongly questions the wisdom of an "all autogenous" policy for reconstruction at this level.
1981年至1989年间,对71例因严重缺血而连续进行的膝上聚四氟乙烯(PTFE)股腘动脉搭桥手术进行了前瞻性随访,以确定移植血管通畅率和肢体挽救情况。通过寿命表分析计算累积移植血管通畅率和肢体挽救率。1年、2年、3年、4年和5年时移植血管通畅率分别为80%、68%、55%、39%和39%,肢体挽救率分别为97%、87%、84%、77%和77%。29条移植血管发生闭塞,其中14例再次出现严重缺血,5例行截肢治疗,9例行重建手术,6例使用自体大隐静脉(ASV),3例使用PTFE。这些良好的结果在原发性通畅方面不如ASV报道的结果,但良好的肢体挽救效果、良好的早期通畅率、易用性以及保留大隐静脉供日后使用,促使我们在部分患者中首选PTFE。这一经验强烈质疑了在此水平重建采用“全自体”策略的合理性。