大肠杆菌无症状菌尿菌株83972的分子特征：病原菌的驯化
Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen.
作者信息
Klemm Per, Roos Viktoria, Ulett Glen C, Svanborg Catharina, Schembri Mark A
机构信息
School of Molecular and Microbial Sciences, Building 76, University of Queensland, Brisbane QLD 4072, Australia.
出版信息
Infect Immun. 2006 Jan;74(1):781-5. doi: 10.1128/IAI.74.1.781-785.2006.
Abstract
Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.
摘要
大肠杆菌83972是一种临床无症状菌尿分离株，能够在人类膀胱中定殖而不引发免疫反应。在此我们证明，该菌株减毒的机制之一是其编码1型菌毛和P菌毛的基因突变。
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