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碘帕醇脊髓造影诱发癫痫发作。

Iopamidol myelography-induced seizures.

作者信息

Singh Sonal, Rajpal Chitra, Nannapeneni Srikanth, Venkatesh Sundar

机构信息

Department of Medicine, Unity Health System, Rochester, New York, USA.

出版信息

MedGenMed. 2005 Apr 11;7(2):11.

Abstract

Iopamidol, a water-soluble contrast agent, has been rarely associated with seizures. We describe a case of generalized tonic-clonic seizure after cervical myelography with iopamidol in a previously healthy young man. In patients presenting with seizures, a history of recent myelography should be considered as an etiology. Iopamidol myelography may be associated with a risk of seizures. Clinicians need to be aware of this complication and inform their patients about such risk.

摘要

碘帕醇是一种水溶性造影剂,很少与癫痫发作相关。我们描述了一例在一名既往健康的年轻男性中,使用碘帕醇进行颈椎脊髓造影后发生全身强直阵挛性发作的病例。对于出现癫痫发作的患者,应考虑近期脊髓造影史作为病因。碘帕醇脊髓造影可能与癫痫发作风险相关。临床医生需要意识到这种并发症,并告知患者此类风险。

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本文引用的文献

1
Status epilepticus and seizures induced by iopamidol myelography.
Seizure. 2004 Apr;13(3):196-9. doi: 10.1016/S1059-1311(03)00077-3.
2
Seizures after myelography with lopamidol.
Am J Emerg Med. 1994 May;12(3):329-30. doi: 10.1016/0735-6757(94)90151-1.
3
Iopamidol 300-induced epilepsy: intensive treatment and pathogenic hypothesis.
Neuroradiology. 1988;30(3):256-7. doi: 10.1007/BF00341838.
4
Seizures following myelography with iopamidol.
Ann Neurol. 1988 Apr;23(4):397-9. doi: 10.1002/ana.410230416.
5
Seizure after intrathecal administration of iopamidol.
AJNR Am J Neuroradiol. 1988 Jul-Aug;9(4):787-8.

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