巨噬细胞电泳迁移率试验在中枢神经系统肿瘤诊断中的应用（作者译）
[Use of the macrophage-electrophoretic-mobility test in the diagnosis of tumours of the central nervous system (author's transl)].
作者信息
Meyer-Rienecker H, Jenssen H L, Köhler H, Günther J K
出版信息
Dtsch Med Wochenschr. 1975 Mar 14;100(11):538-43. doi: 10.1055/s-0028-1106252.
The macrophage-electrophoretic-mobility (MEM) tests of Field and Caspary demonstrates the macrophage-slowing factor (MSF) produced by specifically sentised blood lymphocytes after incubation with the homologous antigen. Besides other diseases with a cellular immune reaction like multiple sclerosis malignant tumours show a reduction of the macrophage mobility in the cell electrophoresis. A significant inhibition in the MEM- test was found in 30 out of 33 tumours of the CNS. Glioblastomas, astrocytomas, spongioblastomas, ependymomas, neurinomas, meningiomas, and a myxofibroma showed a positive result (more than 10% inhibition). The results in ectodermal tumours (pituitary adenoma, craniopharyngioma) differed; secondary brain tumours showed the greatest inhibition.
菲尔德和卡斯帕里的巨噬细胞电泳迁移率（MEM）试验表明，经同源抗原孵育后，特异性致敏血淋巴细胞可产生巨噬细胞趋缓因子（MSF）。除了多发性硬化症等其他具有细胞免疫反应的疾病外，恶性肿瘤在细胞电泳中也显示巨噬细胞迁移率降低。在33例中枢神经系统肿瘤中，有30例在MEM试验中发现有显著抑制作用。胶质母细胞瘤、星形细胞瘤、成胶质细胞瘤、室管膜瘤、神经鞘瘤、脑膜瘤和黏液纤维瘤呈阳性结果（抑制率超过10%）。外胚层肿瘤（垂体腺瘤、颅咽管瘤）的结果有所不同；继发性脑肿瘤的抑制作用最大。
Zotero 插件