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甜菜对四氯化碳诱导的大鼠肝损伤的保肝活性。

Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats.

作者信息

Agarwal M, Srivastava V K, Saxena K K, Kumar A

机构信息

Department of Pharmacology, VMMC and Safdarjung Hospital, New Delhi, India.

出版信息

Fitoterapia. 2006 Feb;77(2):91-3. doi: 10.1016/j.fitote.2005.11.004. Epub 2005 Dec 20.

Abstract

Ethanolic extract of Beta vulgaris roots given orally at doses of 1000, 2000 and 4000 mg/kg exhibited significant dose-dependent hepatoprotective activity against carbontetrachloride (CCl(4))-induced hepatotoxicity in rats. Hepatotoxicity and its prevention were assessed by serum markers viz. cholesterol, triglyceride, alanine amino transferase and alkaline phosphatase.

摘要

以1000、2000和4000毫克/千克剂量口服的甜菜根乙醇提取物对四氯化碳(CCl₄)诱导的大鼠肝毒性表现出显著的剂量依赖性肝保护活性。通过血清标志物即胆固醇、甘油三酯、丙氨酸氨基转移酶和碱性磷酸酶来评估肝毒性及其预防情况。

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