紫铆子对大鼠的抗糖尿病潜力。
Antidiabetic potential of Butea monosperma in rats.
作者信息
Somani Rahul, Kasture Sanjay, Singhai Abhay Kumar
机构信息
NDMVP's College of Pharmacy, Nashik, India.
出版信息
Fitoterapia. 2006 Feb;77(2):86-90. doi: 10.1016/j.fitote.2005.11.003. Epub 2005 Dec 20.
The antihyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced diabetic rats. Repeated oral treatment with BMEE (200 mg/kg/day) for 2 weeks significantly reduced blood glucose, serum cholesterol and improved HDL-cholesterol and albumin as compared to diabetic control group.
研究了紫铆乙醇提取物（BMEE）对葡萄糖负荷和四氧嘧啶诱导的糖尿病大鼠的降血糖活性。单剂量给予BMEE（200mg/kg，口服）可显著改善四氧嘧啶诱导的糖尿病大鼠的葡萄糖耐量，并降低血糖水平。与糖尿病对照组相比，连续2周重复口服BMEE（200mg/kg/天）可显著降低血糖、血清胆固醇，并提高高密度脂蛋白胆固醇和白蛋白水平。
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