Rossell Susan L
Mental Health Research Institute of Victoria, Cognitive Neuropsychiatry, 155 Oak St, Parkville, Melbourne, VIC 3052, Australia.
Schizophr Res. 2006 Feb 28;82(2-3):135-8. doi: 10.1016/j.schres.2005.10.013. Epub 2005 Dec 22.
Semantic fluency (SF) and phonological fluency (PF) were examined in large groups of schizophrenia patients, bipolar patients and controls. As well as standard SF categories (animals and food), fluency to two affective categories, happy and fear was measured, i.e. participants were asked to produce as many words as they could that resulted in or are associated with fear or happiness. Schizophrenia patients showed SF and PF deficits. Bipolar patients showed PF deficits. Thus, PF is argued to be a good cognitive marker in both disorders. Severity of delusions was related to SF performance in all patients. The patient groups showed different patterns on the affective categories compared to controls: the bipolar patients were better and produced more words, especially to the happiness category, and the schizophrenia patients were impaired and produced less words. The results suggest an interesting interaction between psychotic illnesses, fluency and emotion.
对大量精神分裂症患者、双相情感障碍患者和对照组进行了语义流畅性(SF)和语音流畅性(PF)测试。除了标准的SF类别(动物和食物)外,还测量了对两个情感类别(快乐和恐惧)的流畅性,即要求参与者尽可能多地说出引发或与恐惧或快乐相关的单词。精神分裂症患者表现出SF和PF缺陷。双相情感障碍患者表现出PF缺陷。因此,PF被认为是这两种疾病的良好认知标志物。妄想的严重程度与所有患者的SF表现相关。与对照组相比,患者组在情感类别上表现出不同的模式:双相情感障碍患者表现更好,说出的单词更多,尤其是在快乐类别上;而精神分裂症患者则受损,说出的单词更少。结果表明,精神疾病、流畅性和情感之间存在有趣的相互作用。