Walter William L, Clabeaux Jonathan, Wright Timothy M, Walsh William, Walter William K, Sculco Thomas P
Hospital for Special Surgery, New York, New York, USA.
J Arthroplasty. 2005 Dec;20(8):1042-8. doi: 10.1016/j.arth.2005.03.039.
The pumping of fluid and polyethylene wear debris from the joint space to the retroacetabular bone is implicated in the pathogenesis of osteolysis. Three possible mechanisms for this pumping: pressure gradients, diaphragm pumping, and piston pumping were studied in vitro in a laboratory model. The simulated activities of rising from a chair and climbing stairs produced high-pressure gradients and high angles of loading that could pump fluid through the apical hole to the retroacetabular bone. A noncongruent liner acted as a diaphragm pump, producing pressures 6 times higher than that seen with a congruent liner. Pistoning motion of the liner produced pressures 8 times higher than when no pistoning occurs. These pumping mechanisms could be mitigated by the use of acetabular components without holes.
关节腔内的液体和聚乙烯磨损碎屑被泵送至髋臼后骨与骨质溶解的发病机制有关。在实验室模型中对这种泵送的三种可能机制:压力梯度、隔膜泵作用和活塞泵作用进行了体外研究。从椅子上起身和爬楼梯的模拟活动产生了高压梯度和高加载角度,可将液体通过顶端孔泵送至髋臼后骨。不相配的内衬起到隔膜泵的作用,产生的压力比相配内衬高6倍。内衬的活塞运动产生的压力比不发生活塞运动时高8倍。使用无孔的髋臼组件可减轻这些泵送机制。