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非骨水泥髋臼假体术后负重导致的机械接触丧失:一种生物力学模型

Loss in mechanical contact of cementless acetabular prostheses due to post-operative weight bearing: a biomechanical model.

作者信息

Bellini Chiara Maria, Galbusera Fabio, Ceroni Roberto Giacometti, Raimondi Manuela Teresa

机构信息

Laboratory of Biological Structure Mechanics, Politecnico di Milano, Milan, Italy.

出版信息

Med Eng Phys. 2007 Mar;29(2):175-81. doi: 10.1016/j.medengphy.2006.02.008. Epub 2006 Mar 29.

Abstract

The primary stability of cementless acetabular components is a prerequisite for their clinical success. The target of the present study was to analyse possible effects of post-operative joint loading on the initial mechanical stability of a press-fitted acetabular prosthesis. For this purpose, a three-dimensional finite element model of the pelvic bone with acetabular reconstruction was set-up. The analysis included two steps: (1) simulation of the prosthesis press-fit implantation and (2) simulation of the instant of peak resultant hip loading during the one-legged stance. The difference between the contact pressures at the bone/implant interface, at the end of the second step and those at the end of the first step was calculated and assumed as an index of variation in mechanical contact due to post-operative weight bearing. The results show that, due to hip loading, contact pressures given by press-fit increase in the postero-superior acetabular region but decrease in the antero-inferior acetabular region. The calculated area in which the contact pressures decrease extend to about 30% of the total contact surface. These results imply that post-operative joint loading significantly reduces the mechanical stability given by press-fit. The decrease in contact pressures at the bone/implant interface may result in a lack of osteointegration, possibly hindering the implant secondary stability. It may also create a route for wear debris, possibly favouring periprosthetic osteolysis, which may lead to further loss in contact and clinical failure of the implant due to loosening.

摘要

非骨水泥型髋臼部件的初始稳定性是其临床成功的前提条件。本研究的目的是分析术后关节负荷对压配式髋臼假体初始机械稳定性的可能影响。为此,建立了一个髋臼重建的骨盆骨三维有限元模型。分析包括两个步骤:(1)假体压配植入的模拟和(2)单腿站立时髋关节负荷峰值瞬间的模拟。计算第二步结束时与第一步结束时骨/植入物界面处接触压力的差值,并将其作为术后负重导致机械接触变化的指标。结果表明,由于髋关节负荷,压配产生的接触压力在髋臼后上区域增加,而在髋臼前下区域减小。计算得出接触压力降低的区域延伸至总接触面积的约30%。这些结果表明,术后关节负荷显著降低了压配所提供的机械稳定性。骨/植入物界面处接触压力的降低可能导致骨整合不足,可能会阻碍植入物的二期稳定性。它还可能为磨损碎屑创造一条路径,可能会促进假体周围骨溶解,这可能会导致接触进一步丧失以及植入物因松动而出现临床失败。

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