糖代谢受损人群的视网膜病变：澳大利亚糖尿病、肥胖与生活方式（AusDiab）研究
Retinopathy in persons with impaired glucose metabolism: the Australian Diabetes Obesity and Lifestyle (AusDiab) study.
作者信息
Wong Tien Y, Barr Elizabeth L M, Tapp Robyn J, Harper C Alex, Taylor Hugh R, Zimmet Paul Z, Shaw Jonathan E
机构信息
Centre for Eye Research Australia, University of Melbourne, 32 Gisborne Street, Melbourne, Victoria 3002, Australia.
出版信息
Am J Ophthalmol. 2005 Dec;140(6):1157-9. doi: 10.1016/j.ajo.2005.07.030.
PURPOSE
To describe risk factors and vascular disease associations of retinopathy in people with impaired glucose metabolism.
DESIGN
Population-based cross-sectional study.
METHODS
Retinal photographs taken of participants with impaired glucose tolerance and impaired fasting glucose were graded for retinopathy. Risk factors and cardiovascular outcomes were ascertained.
RESULTS
Retinopathy was present in 69 (6.7%) of 1027 participants with impaired glucose tolerance or impaired fasting glucose. After multivariate adjustment, retinopathy was associated with prevalent stroke (odds ratio 4.2, 95% confidence interval, 1.8 to 9.7).
CONCLUSIONS
Retinopathy is common in persons with impaired glucose metabolism and may be associated with prevalent stroke.
目的
描述糖代谢受损人群视网膜病变的危险因素及与血管疾病的关联。
设计
基于人群的横断面研究。
方法
对糖耐量受损和空腹血糖受损参与者拍摄的视网膜照片进行视网膜病变分级。确定危险因素和心血管结局。
结果
1027例糖耐量受损或空腹血糖受损参与者中，69例（6.7%）存在视网膜病变。多因素调整后，视网膜病变与既往中风相关（比值比4.2，95%置信区间1.8至9.7）。
结论
视网膜病变在糖代谢受损人群中很常见，可能与既往中风有关。
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