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[脊髓麻醉后体温过低:吗啡的影响?]

[Hypothermia after spinal anaesthesia: implication of morphine?].

作者信息

Fischer M O, Dequiré P-M, Kalem A, Gérard J L, Plaud B

机构信息

Département d'anesthésie-réanimation chirurgicale, Samu, CHU de Côte-de-Nacre, Caen, France.

出版信息

Ann Fr Anesth Reanim. 2006 Mar;25(3):296-8. doi: 10.1016/j.annfar.2005.09.009. Epub 2005 Dec 27.

DOI:10.1016/j.annfar.2005.09.009
PMID:16377124
Abstract

Spinal anaesthesia is the gold standard for elective caesarean section. This technique presents several adverse effects. We report a severe case of hypothermia (33.3 degrees C) after spinal administration of bupivacaine (10 mg) and morphine (100 microg) for elective caesarean section. After excluding other causes of hypothermia, this one could be explained by both the own effects of local anaesthesia (i.e. peripheral vasodilatation) and by the central effect of intrathecal morphine. Because hypothermia is not predictable after spinal injection of morphine both monitoring of central temperature and active warming of the patients could be proposed. Naloxone has been proposed in a case of hypothermia related to spinal injection of morphine.

摘要

脊髓麻醉是择期剖宫产的金标准。该技术存在多种不良反应。我们报告了一例择期剖宫产患者在脊髓注射布比卡因(10毫克)和吗啡(100微克)后发生严重体温过低(33.3摄氏度)的病例。在排除其他体温过低的原因后,这一情况可由局部麻醉本身的作用(即外周血管扩张)以及鞘内注射吗啡的中枢作用来解释。由于脊髓注射吗啡后体温过低无法预测,因此建议对患者进行中心体温监测并积极保暖。对于与脊髓注射吗啡相关的体温过低病例,有人提出使用纳洛酮。

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1
[Hypothermia after spinal anaesthesia: implication of morphine?].[脊髓麻醉后体温过低:吗啡的影响?]
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A randomised double-blind controlled study evaluating the hypothermic effect of 150 microg morphine during spinal anaesthesia for Caesarean section.一项评估150微克吗啡在剖宫产脊髓麻醉期间低温效应的随机双盲对照研究。
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Hypothermia after cesarean delivery and its reversal with lorazepam.剖宫产术后体温过低及其用劳拉西泮的逆转。
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[Does combination of intrathecal magnesium sulfate and morphine improve postcaesarean section analgesia?].鞘内注射硫酸镁与吗啡联合使用是否能改善剖宫产术后镇痛?
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Hypothermia and excessive sweating following intrathecal morphine in a parturient undergoing cesarean delivery.剖宫产分娩产妇鞘内注射吗啡后出现体温过低和多汗。
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Comparison of the effects of intrathecal morphine and pethidine on shivering after Caesarean delivery under combined-spinal epidural anaesthesia.腰麻-硬膜外联合麻醉下剖宫产术后鞘内注射吗啡和哌替啶对寒战影响的比较
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The effects of sufentanil or morphine added to hyperbaric bupivacaine in spinal anaesthesia for caesarean section.剖宫产脊髓麻醉中,舒芬太尼或吗啡添加至高压布比卡因中的效果。
Eur J Anaesthesiol. 2006 Apr;23(4):285-91. doi: 10.1017/S0265021505001869. Epub 2006 Jan 27.

引用本文的文献

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Morphine-induced fever: a case report and review of the literature.吗啡诱导性发热:病例报告及文献复习。
J Med Case Rep. 2024 Sep 27;18(1):449. doi: 10.1186/s13256-024-04770-2.
2
Continuous spinal anesthesia with sufentanil in labor analgesia can induce maternal febrile responses in puerperas.分娩镇痛中使用舒芬太尼进行连续脊髓麻醉可诱发产妇发热反应。
Int J Clin Exp Med. 2013 May 22;6(5):334-41. Print 2013.