Stover Nicholas A, Krieger Cynthia J, Binkley Gail, Dong Qing, Fisk Dianna G, Nash Robert, Sethuraman Anand, Weng Shuai, Cherry J Michael
Department of Genetics, School of Medicine, Stanford University, Stanford, CA 94305-5120, USA.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D500-3. doi: 10.1093/nar/gkj054.
We have developed a web-based resource (available at www.ciliate.org) for researchers studying the model ciliate organism Tetrahymena thermophila. Employing the underlying database structure and programming of the Saccharomyces Genome Database, the Tetrahymena Genome Database (TGD) integrates the wealth of knowledge generated by the Tetrahymena research community about genome structure, genes and gene products with the newly sequenced macronuclear genome determined by The Institute for Genomic Research (TIGR). TGD provides information curated from the literature about each published gene, including a standardized gene name, a link to the genomic locus in our graphical genome browser, gene product annotations utilizing the Gene Ontology, links to published literature about the gene and more. TGD also displays automatic annotations generated for the gene models predicted by TIGR. A variety of tools are available at TGD for searching the Tetrahymena genome, its literature and information about members of the research community.
我们为研究模式纤毛虫嗜热四膜虫的研究人员开发了一个基于网络的资源（可在www.ciliate.org获取）。利用酿酒酵母基因组数据库的基础数据库结构和编程，四膜虫基因组数据库（TGD）将四膜虫研究群体产生的关于基因组结构、基因和基因产物的丰富知识与基因组研究所（TIGR）新测序的大核基因组整合在一起。TGD提供从文献中整理出的关于每个已发表基因的信息，包括标准化的基因名称、在我们的图形化基因组浏览器中到基因组位点的链接、利用基因本体论的基因产物注释、到关于该基因的已发表文献的链接等等。TGD还显示为TIGR预测的基因模型生成的自动注释。TGD提供了多种工具，用于搜索四膜虫基因组、其文献以及有关研究群体成员的信息。
