Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.
Sci China Life Sci. 2011 Jan;54(1):65-7. doi: 10.1007/s11427-010-4114-1. Epub 2011 Jan 21.
Tetrahymena thermophila is a model eukaryotic organism. Functional genomic analyses in Tetrahymena present rich opportunities to address fundamental questions of cell and molecular biology. The Tetrahymena Gene Expression Database (TGED; available at http://tged.ihb.ac.cn) is the first expression database of a ciliated protozoan. It covers three major physiological and developmental states: growth, starvation, and conjugation, and can be accessed through a user-friendly web interface. The gene expression profiles and candidate co-expressed genes for each gene can be retrieved using Gene ID or Gene description searches. Descriptions of standardized methods of sample preparation and the opportunity to add new Tetrahymena microarray data will be of great interest to the Tetrahymena research community. TGED is intended to be a resource for all members of the scientific research community who are interested in Tetrahymena and other ciliates.
嗜热四膜虫是一种模式真核生物。嗜热四膜虫的功能基因组分析为解决细胞和分子生物学的基本问题提供了丰富的机会。嗜热四膜虫基因表达数据库（TGED；可在 http://tged.ihb.ac.cn 获得）是首个纤毛原生动物的表达数据库。它涵盖了三个主要的生理和发育状态：生长、饥饿和接合，并可以通过用户友好的网络界面进行访问。使用基因 ID 或基因描述搜索，可以检索到每个基因的基因表达谱和候选共表达基因。有关样品制备标准化方法的说明以及添加新的嗜热四膜虫微阵列数据的机会，将引起嗜热四膜虫研究界的极大兴趣。TGED 旨在成为对嗜热四膜虫和其他纤毛虫感兴趣的所有科学研究界成员的资源。
