Tiryaki Ozlem, Buyukhatipoglu Hakan, Karakok Metin, Usalan Celalettin
Department of Nephrology, Gaziantep University School of Medicine, Gaziantep, Turkey.
Intern Med. 2007;46(12):905-7. doi: 10.2169/internalmedicine.46.6272. Epub 2007 Jun 15.
Henoch-Schönlein purpura (HSP) is a form of systemic vasculitis involving both arterioles and capillaries. HSP frequently is seen in children between the ages of 2 and 11 years, though adults with this disease are occasionally encountered. Although it primarily is a disease of early childhood, it can occur at any age. The clinical manifestations include a classic tetrad: rash, arthralgias, abdominal pain and renal disease. However, it may affect almost any other bodily tissue, such as myocardium, lungs, ureter and nervous system. Pulmonary hemorrhage is a rare complication of HSP, which largely has been observed in adolescents and adults. Pulmonary hemorrhage in HSP is associated with significant morbidity and mortality. We present the successful treatment of a 78-year-old woman with HSP complicated by pulmonary hemorrhage.
过敏性紫癜(HSP)是一种累及小动脉和毛细血管的系统性血管炎。HSP常见于2至11岁的儿童,不过偶尔也会遇到患有这种疾病的成年人。虽然它主要是一种儿童早期疾病,但可发生于任何年龄。临床表现包括典型的四联征:皮疹、关节痛、腹痛和肾脏疾病。然而,它几乎可能影响任何其他身体组织,如心肌、肺、输尿管和神经系统。肺出血是HSP的一种罕见并发症,主要在青少年和成年人中观察到。HSP中的肺出血与显著的发病率和死亡率相关。我们报告了一例成功治疗的78岁女性过敏性紫癜合并肺出血病例。