Dynnik O B, Gavrilenko T I, Zalesskiĭ V N
Lik Sprava. 2005 Jul-Sep(5-6):3-10.
A literature review considers apoptosis-related immunological aspects of chronic heart failure (CHF). Scientific data on the induction of cardiomiocyte apoptosis, NO and immune factors--cytokines in the development of CHF and remodeling of myocardium were analyzed. Modern approaches of therapy for patients with CHF were discussed in the article. They include combined correction of functioning mechanisms of neurohumoral systems and elimination of adverse effects of apoptosis--associated cytokine "aggression".
一篇文献综述探讨了慢性心力衰竭（CHF）中与细胞凋亡相关的免疫学方面。分析了有关心肌细胞凋亡诱导、一氧化氮（NO）以及免疫因子——细胞因子在CHF发展和心肌重塑过程中的科学数据。文章还讨论了CHF患者的现代治疗方法。这些方法包括对神经体液系统功能机制的联合纠正以及消除与细胞凋亡相关的细胞因子“侵袭”的不良影响。
