Suppr超能文献

[神经性疼痛:背景、新工具、新药]

[Neuropathic pains: background, new tools, new drugs].

作者信息

Kuntzer Thierry, Decosterd Isabelle

机构信息

Unité nerf-muscle, Service de neurologie, CHUV, 1011 Lausanne.

出版信息

Rev Med Suisse. 2005 Nov 30;1(43):2812-6.

Abstract

Neuropathic pains are frequent with better understood underlying mechanisms. The introduction of a new questionnaire, named DN4 (neuropathic pain 4 questions) will certainly be useful to prevent persistent pain. Here we describe current approaches to diagnosis and pharmacological treatments. Antidepressants, anticonvulsants, opioids and topical local anesthetics are part of the evidence-based approach, alone or in combination. The choice of the drug is based on the type of pain, a predominantly diffused pain being firstly treated with tricyclic antidepressants, whereas paroxysmal and localized pain being more adequately treated with anti-epileptics. Pregabaline, the newest anticonvulsant launched in the Swiss market, appears to be effective as a treatment of painful diabetic polyneuropathy and postherpetic neuralgia.

摘要

神经病理性疼痛很常见,其潜在机制也得到了更好的理解。一种名为DN4(神经病理性疼痛4个问题)的新问卷的引入,对于预防持续性疼痛肯定会很有用。在此,我们描述当前的诊断方法和药物治疗方法。抗抑郁药、抗惊厥药、阿片类药物和局部外用麻醉剂是循证治疗方法的一部分,可单独使用或联合使用。药物的选择基于疼痛类型,弥漫性为主的疼痛首先用三环类抗抑郁药治疗,而阵发性和局部性疼痛用抗癫痫药治疗更为合适。普瑞巴林是瑞士市场上推出的最新抗惊厥药,似乎对治疗糖尿病性周围神经病变性疼痛和带状疱疹后神经痛有效。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验