脊髓损伤中血液酒精浓度与损伤严重程度的关系。
The relationship of blood alcohol concentration to impairment severity in spinal cord injury.
作者信息
Forchheimer Martin, Cunningham Rebecca M, Gater David R, Maio Ronald F
机构信息
University of Michigan, Model Spinal Cord Injury Care System, Department of Physical Medicine and Rehabilitation, Ann Arbor, MI 48109-0419, USA.
出版信息
J Spinal Cord Med. 2005;28(4):303-7. doi: 10.1080/10790268.2005.11753824.
OBJECTIVE
To investigate the relationship between blood alcohol concentration (BAC) and severity of neurological impairment.
DESIGN
Retrospective cross-sectional study.
PARTICIPANTS
Subjects with traumatic spinal cord injury (SCI; N = 119) with dates of injury between 1991 and 2000 who received their acute treatment at a midwestern Model SCI Care System and for whom information regarding BAC was available.
MAIN OUTCOME MEASURE
severity of neurological impairment. Data were analyzed using chi2 tests and analysis of variance (ANOVA).
RESULTS
A significant association was observed between impairment severity and BAC.
CONCLUSIONS
The study suggests that alcohol consumption is associated with severity of SCI. A more rigorous study controlling for trauma attributes is necessary to confirm these results and appraise whether alcohol has a potentiating effect on impairment. If borne out, the study's findings may lead to alterations in emergency room procedures and to changes in public health and education efforts resulting from a reframing of the issue of safe consumption of alcohol.
目的
研究血液酒精浓度（BAC）与神经功能损害严重程度之间的关系。
设计
回顾性横断面研究。
参与者
1991年至2000年间在中西部脊髓损伤模范护理系统接受急性治疗且有血液酒精浓度信息的创伤性脊髓损伤（SCI）患者（N = 119）。
主要观察指标
神经功能损害的严重程度。数据采用卡方检验和方差分析（ANOVA）进行分析。
结果
观察到损害严重程度与血液酒精浓度之间存在显著关联。
结论
该研究表明饮酒与脊髓损伤的严重程度相关。需要进行一项更严格的研究，控制创伤因素，以证实这些结果并评估酒精是否对损伤有增强作用。如果得到证实，该研究结果可能会导致急诊室程序的改变，以及由于重新审视酒精安全消费问题而引起的公共卫生和教育工作的变化。
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