巴氯芬泵干预对影响肺功能的痉挛的作用
Baclofen pump intervention for spasticity affecting pulmonary function.
作者信息
Britton Deanna, Goldstein Barry, Jones-Redmond Jill, Esselman Peter
机构信息
Speech-Language Pathology Clinical Specialist, Harborview Medical Center, 325 Ninth Avenue, Box 359819, Seattle, WA 98104, USA.
出版信息
J Spinal Cord Med. 2005;28(4):343-7. doi: 10.1080/10790268.2005.11753832.
Abstract
INTRODUCTION
Muscle spasticity may adversely affect pulmonary function after spinal cord injury (SCI). However, there is limited information regarding the treatment of spasticity as a determinant of pulmonary function. This study presents the case of a man with C4 tetraplegia who had severe spasticity and difficulty weaning from ventilatory support.
METHODS
Case presentation.
RESULTS
Severe spasticity likely contributed to respiratory compromise in this patient. Successful and rapid weaning from the ventilator occurred within 3 weeks of baclofen pump placement.
CONCLUSIONS
Randomized clinical trials among SCI patients with significant spasticity are needed to determine whether intervention with a baclofen pump facilitates earlier ventilatory weaning.
摘要
引言
脊髓损伤（SCI）后肌肉痉挛可能会对肺功能产生不利影响。然而，关于将痉挛治疗作为肺功能决定因素的相关信息有限。本研究报告了一名患有C4四肢瘫痪的男性病例，该患者存在严重痉挛且脱机困难。
方法
病例报告。
结果
严重痉挛可能导致了该患者的呼吸功能不全。在植入巴氯芬泵后3周内成功且迅速地实现了脱机。
结论
需要在有明显痉挛的脊髓损伤患者中进行随机临床试验，以确定巴氯芬泵干预是否有助于更早地脱机。
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