Zoega Gunnar Már, Gunnarsdóttir Thornóra, Björnsdóttir Sigríethur, Hreietharsson Astradur B, Viggósson Guethmundur, Stefánsson Einar
Department of Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland.
Acta Ophthalmol Scand. 2005 Dec;83(6):687-90. doi: 10.1111/j.1600-0420.2005.00541.x.
To study the relationship between screening compliance and visual outcome in a screening programme for diabetic eye disease.
A retrospective case control study. The screening compliance of all the diabetes patients (n = 22) listed at the Icelandic National Registry for the Blind (visual acuity <0.3) was compared to a matched group of 44 non-blind diabetes patients (visual acuity > or =0.3) who participated in the same screening programme for diabetic retinopathy. Glycaemic control (HbA1c), office blood pressure and cholesterol levels were assessed.
The study group had a significantly lower level of compliance with the screening programme (27% +/- 38% [mean +/- SD] versus 77% +/- 26% [mean +/- SD]; p < 0.0001). Macular oedema or proliferative diabetic retinopathy was found in 60% (13/22) of the study group when entering the screening programme, compared to 7% (3/44) in the control group. Blood pressure (except diastolic BP among type 1 diabetes mellitus), blood glucose and cholesterol levels were identical. The prevalence of blindness and low vision amongst diabetes patients in Iceland is about 0.5%.
There was a significant relationship between screening compliance and visual outcome in diabetes patients in our screening programme.
研究糖尿病眼病筛查项目中筛查依从性与视力结果之间的关系。
一项回顾性病例对照研究。将冰岛国家盲人登记处列出的所有糖尿病患者(n = 22,视力<0.3)的筛查依从性与一组44名非盲人糖尿病患者(视力≥0.3)的筛查依从性进行比较,这组非盲人糖尿病患者参与了相同的糖尿病视网膜病变筛查项目。评估血糖控制(糖化血红蛋白)、诊室血压和胆固醇水平。
研究组对筛查项目的依从性显著较低(27%±38%[均值±标准差]对77%±26%[均值±标准差];p<0.0001)。进入筛查项目时,研究组60%(13/22)的患者发现有黄斑水肿或增殖性糖尿病视网膜病变,而对照组为7%(3/44)。血压(1型糖尿病患者的舒张压除外)、血糖和胆固醇水平相同。冰岛糖尿病患者中失明和低视力的患病率约为0.5%。
在我们的筛查项目中,糖尿病患者的筛查依从性与视力结果之间存在显著关系。