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心肺复苏期间药物治疗中的争议问题。

Controversial issues in drug treatment during cardiopulmonary resuscitation.

作者信息

Van Pelt D R, Wingfield W E

机构信息

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.

出版信息

J Am Vet Med Assoc. 1992 Jun 15;200(12):1938-44.

PMID:1639699
Abstract

The goal of advanced life support in CPR must be to restore and maintain respiratory and hemodynamic effectiveness, and to correct the underlying dysrhythmia. Optimal basic life-support techniques must be continued to meet these goals. Many drugs have been suggested in the treatment of cardiac arrest, but unfortunately, drug effects are inconsistent and resuscitation rates remain low. Epinephrine, atropine, lidocaine, bretylium, and naloxone remain important drugs for consideration in CPR in most animals with cardiac arrest. The best chance of survival remains in early recognition of animals susceptible to arrest and in treatment of the underlying cause.

摘要

心肺复苏中高级生命支持的目标必须是恢复并维持呼吸和血流动力学的有效性,并纠正潜在的心律失常。必须持续采用最佳的基本生命支持技术以实现这些目标。在心脏骤停的治疗中,人们已提出了许多药物,但遗憾的是,药物效果并不一致,复苏率仍然很低。对于大多数心脏骤停的动物,肾上腺素、阿托品、利多卡因、溴苄铵和纳洛酮仍是心肺复苏中值得考虑的重要药物。存活的最佳机会在于早期识别易发生心脏骤停的动物并治疗潜在病因。

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