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也门食管癌经裂孔与经胸切除术的比较

Transhiatal versus transthoracic resection for oesophageal carcinoma in Yemen.

作者信息

Homesh N A, Alsabahi A A, Al-Agmar M H, Alwashaly A A, Valenzuela R E, Alhadid M A, Alkubati S M

机构信息

Department of Surgery, Sana'a University and Al-Thawra Teaching Hospital, P O Box 1596, Sana'a, Yemen.

出版信息

Singapore Med J. 2006 Jan;47(1):54-9.

Abstract

INTRODUCTION

Cancer of the oesophagus is a major problem in Yemen, where most of the patients present with advanced disease. Curative oesophageal resection for carcinoma may be carried out by either the transhiatal or transthoracic technique. The aims of this study were to compare the morbidity, mortality, short term outcome and long term survival of the two techniques in the treatment of oesophageal carcinoma.

METHODS

From March 1998 to July 2004,118 patients with cancer of the oesophagus were studied. The tumours in 84 patients were resected by transhiatal oesophagectomy (43) and transthoracic oesophagectomy (41).

RESULTS

The two groups were comparable in terms of age, sex, location of the tumours, risk factors and stage of the disease. There was no significant difference in the mean intensive care unit stay, blood transfusion and mean hospital stay. Anastomotic leak was higher in the transhiatal oesophagectomy group than transthoracic group (21 percent versus 12 percent, p-value is equal to 0.001). Recurrent laryngeal nerve lesion was present in 18.6 percent of the transhiatal group and absent in the transthoracic group. The overall hospital mortality was 8.3 percent with no significant difference between the two groups (transhiatal 9.3 percent versus transthoracic 7.3 percent, p-value is equal to 0.742).

CONCLUSION

Transhiatal oesophagectomy was associated with a higher incidence of anastomotic complications and recurrent laryngeal nerve lesions, but there was no significant difference in the mortality between the two groups.

摘要

引言

食道癌在也门是一个主要问题,该国大多数患者就诊时已处于疾病晚期。食管癌的根治性食管切除术可通过经裂孔或经胸技术进行。本研究的目的是比较这两种技术治疗食管癌的发病率、死亡率、短期结局和长期生存率。

方法

1998年3月至2004年7月,对118例食管癌患者进行了研究。84例患者的肿瘤通过经裂孔食管切除术(43例)和经胸食管切除术(41例)切除。

结果

两组在年龄、性别、肿瘤位置、危险因素和疾病分期方面具有可比性。重症监护病房平均住院时间、输血情况和平均住院时间无显著差异。经裂孔食管切除术组的吻合口漏发生率高于经胸组(21%对12%,p值等于0.001)。经裂孔组18.6%出现喉返神经损伤,经胸组未出现。总体医院死亡率为8.3%,两组之间无显著差异(经裂孔组9.3%对经胸组7.3%,p值等于0.742)。

结论

经裂孔食管切除术与吻合口并发症和喉返神经损伤的发生率较高相关,但两组之间的死亡率无显著差异。

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