Erdemoglu Nurgun, Turan Nilufer N, Cakici Iclal, Sener Bilge, Aydin Ahmet
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330 Ankara, Turkey.
Phytother Res. 2006 Jan;20(1):9-13. doi: 10.1002/ptr.1816.
The antioxidant activities of four Lamiaceae plants, Salvia viridis L., Salvia multicaulis Vahl, Stachys byzantina C. Koch and Eremostachys laciniata (L.) Bunge have been determined by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as well as by flow injection analysis-luminol chemiluminescence (FIA-CL). All extracts were shown to possess a significant scavenger activity against DPPH free radical and an inhibitory effect on H2O2- or HOCl-luminol chemiluminescence. The extracts scavenged 50% of DPPH radical ranging in the following descending order: Salvia viridis > Stachys byzantina > Salvia multicaulis > Eremostachys laciniata. The most potent extract on H2O2-induced peak chemiluminescence was that of Salvia viridis and on HOCl-induced peak chemiluminescence was that of Stachys byzantina. The results concluded that the extracts have a potential source of antioxidants of natural origin.
通过使用1,1-二苯基-2-苦基肼(DPPH)以及流动注射分析-鲁米诺化学发光法(FIA-CL),测定了四种唇形科植物—— 绿花鼠尾草(Salvia viridis L.)、多茎鼠尾草(Salvia multicaulis Vahl)、绵毛水苏(Stachys byzantina C. Koch)和裂叶沙穗(Eremostachys laciniata (L.) Bunge)的抗氧化活性。结果表明,所有提取物均对DPPH自由基具有显著的清除活性,并对H2O2或HOCl-鲁米诺化学发光具有抑制作用。提取物清除50% DPPH自由基的能力排序如下(从高到低):绿花鼠尾草 > 绵毛水苏 > 多茎鼠尾草 > 裂叶沙穗。对H2O2诱导的峰值化学发光抑制作用最强的提取物来自绿花鼠尾草,而对HOCl诱导的峰值化学发光抑制作用最强的提取物来自绵毛水苏。结果表明,这些提取物是天然抗氧化剂的潜在来源。