Transplant Research Center, Clinical Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Radiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Curr Pharm Biotechnol. 2024;25(5):534-562. doi: 10.2174/1389201024666230714143538.
Neuropathic pain is a disabling condition caused by various diseases and can profoundly impact the quality of life. Unfortunately, current treatments often do not produce complete amelioration and can be associated with potential side effects. Recently, herbal drugs have garnered more attention as an alternative or a complementary treatment. In this article, we summarized the results of randomized clinical trials to evaluate the effects of various phytomedicines on neuropathic pain. In addition, we discussed their main bioactive components and potential mechanisms of action to provide a better view of the application of herbal drugs for treating neuropathic pain.
神经病理性疼痛是一种由多种疾病引起的致残性疾病，可极大地影响生活质量。遗憾的是，目前的治疗方法往往不能完全缓解疼痛，且可能存在潜在的副作用。最近，草药药物作为一种替代或补充治疗方法受到了更多关注。在本文中，我们总结了评估各种植物药治疗神经病理性疼痛的随机临床试验结果。此外，我们还讨论了它们的主要生物活性成分和潜在的作用机制，以期更好地了解草药药物治疗神经病理性疼痛的应用。
