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白内障手术对老年人认知功能的影响。

Effect of cataract surgery on cognitive function in older adults.

作者信息

Hall Tyler Andrew, McGwin Gerald, Owsley Cynthia

机构信息

Department of Ophthalmology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

出版信息

J Am Geriatr Soc. 2005 Dec;53(12):2140-4. doi: 10.1111/j.1532-5415.2005.00499.x.

Abstract

OBJECTIVES

To assess whether cataract surgery has an effect on cognitive function in older adults.

DESIGN

Longitudinal.

SETTING

Assessment of patients seen in eye clinics.

PARTICIPANTS

Patients with no cataract (n=92), patients with cataract who elected surgery (n=122), and patients with cataract who declined surgery (n=87).

MEASUREMENTS

At baseline and 1-year follow-up visits, the following information was obtained: demographic, health behavior, general health status, medication use, depressive symptoms, cognitive function, and visual function information. This information was compared within and between groups at baseline and follow-up visits.

RESULTS

Mattis Organic Mental Syndrome Screening Examination scores at baseline and follow-up varied across the three groups, with the cataract/no surgery group having the highest scores (more cognitive impairment) and the no-cataract group having the lowest scores (less cognitive impairment). For the within-group analysis, at follow-up, the cataract/no surgery group and the cataract/surgery group had significantly less cognitive impairment (P<.001), whereas the no-cataract group experienced no change. For those with cataract, there were no associations between changes in visual function and cognitive function.

CONCLUSION

Improvement in cognitive function may occur after cataract surgery but cannot be attributed to the cataract surgery per se or to improved visual function. Clinicians may find this information useful when discussing the nonvisual outcomes of cataract surgery with patients.

摘要

目的

评估白内障手术对老年人认知功能是否有影响。

设计

纵向研究。

地点

眼科诊所对患者的评估。

参与者

无白内障患者(n = 92)、选择手术的白内障患者(n = 122)和拒绝手术的白内障患者(n = 87)。

测量

在基线和1年随访时,获取以下信息:人口统计学、健康行为、总体健康状况、用药情况、抑郁症状、认知功能和视觉功能信息。在基线和随访时对组内和组间的这些信息进行比较。

结果

三组在基线和随访时的马蒂斯器质性精神综合征筛查检查得分各不相同,白内障/未手术组得分最高(认知障碍更严重),无白内障组得分最低(认知障碍较轻)。对于组内分析,随访时,白内障/未手术组和白内障/手术组的认知障碍明显减轻(P <.001),而无白内障组无变化。对于白内障患者,视觉功能变化与认知功能之间无关联。

结论

白内障手术后认知功能可能会改善,但不能归因于白内障手术本身或视觉功能改善。临床医生在与患者讨论白内障手术的非视觉结果时可能会发现此信息有用。

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