Kumar S G Prem, Vishwakarma Pankaj, Ranpise Dhanaji, Chavan Shobhana, Krishnan Radhika, Kurian Elizabeth
Mission for Vision, Nariman Point, Mumbai, Maharashtra, India.
Aditya Jyot Foundation for Twinkling Little Eyesl, Mumbai, Maharashtra, India.
Indian J Psychol Med. 2023 Nov;45(6):598-609. doi: 10.1177/02537176231172300. Epub 2023 Jun 11.
Systematic data on mental health issues among adults with cataracts are not available from India. This study explored the impact of cataract surgery on depressive and generalized anxiety (GA) symptoms in an adult Indian sample.
A multicenter, prospective, longitudinal cohort study was conducted. Subjects were recruited from four tertiary eye hospitals to assess depression, GA, and associated risk factors. A follow-up survey was carried out at 6 ( = 273, group 1), 12 ( = 198, group 2), or 18 months ( = 105, group 3) post-cataract surgery. Variations in the intensity of depression and GA were assessed using multiple classification analysis (MCA).
A total of 576 patients completed both baseline and follow-up assessments. The mean (SD) depression score was 25.6 (8.5) before surgery and 8.6 (7.7), 9.9 (7), and 9.8 (6.8), respectively, post-surgery for the three groups on the Center for Epidemiologic Studies Depression scale (CES-D). The mean GA score was 6.7 (4.2) at baseline and 1.1 (2.3), 1 (1.8), and 0.6 (1.3) after surgery on the Generalized Anxiety Disorder scale (GAD-7). MCA showed that factors with the highest impact on the mean change scores for both depressive and GA symptoms were restoration of vision post-surgery ( = 0.381 and 0.185) in group 1, regaining functional independence and female sex in group 2 ( = 0.192 and 0.23), and the presence of ocular comorbidities in the fellow eye ( = 0.36 and 0.315) in group 3.
Mental health symptoms improved significantly post-cataract surgery across the three groups. The urgent need to invest in strategies that enable early cataract case detection and treat ocular anomalies in the fellow eye is highlighted.
印度尚无关于白内障成年患者心理健康问题的系统性数据。本研究探讨了白内障手术对成年印度样本中抑郁和广泛性焦虑（GA）症状的影响。
开展了一项多中心、前瞻性纵向队列研究。从四家三级眼科医院招募受试者，以评估抑郁、GA及相关危险因素。在白内障手术后6个月（n = 273，第1组）、12个月（n = 198，第2组）或18个月（n = 105，第3组）进行随访调查。使用多重分类分析（MCA）评估抑郁和GA强度的变化。
共有576例患者完成了基线和随访评估。在流行病学研究中心抑郁量表（CES - D）上，三组患者术前抑郁评分均值（标准差）为25.6（8.5），术后分别为8.6（7.7）、9.9（7）和9.8（6.8）。在广泛性焦虑障碍量表（GAD - 7）上，基线时GA评分均值为6.7（4.2），术后为1.1（2.3）、1（1.8）和0.6（1.3）。MCA显示，对抑郁和GA症状平均变化评分影响最大的因素在第1组是术后视力恢复（β = 0.381和0.185），第2组是恢复功能独立性和女性性别（β = 0.192和0.23），第3组是对侧眼存在眼部合并症（β = 0.36和0.315）。
三组患者白内障手术后心理健康症状均显著改善。强调了迫切需要投入策略以实现早期白内障病例检测并治疗对侧眼的眼部异常。
