Lorenzen Janne K, Mølgaard Christian, Michaelsen Kim F, Astrup Arne
Department of Human Nutrition, Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Am J Clin Nutr. 2006 Jan;83(1):18-23. doi: 10.1093/ajcn/83.1.18.
Accumulating evidence from observational studies indicates that a high calcium intake may reduce body weight and body fat. However, few randomized trials have been conducted.
We examined whether calcium supplementation affects body weight and body fat in young girls and whether a relation exists between habitual calcium intake and body weight and body fat.
A randomized, double-blind, placebo-controlled intervention study was conducted in 110 young girls. The subjects were randomly assigned to receive 500 mg Ca/d as calcium carbonate or placebo for 1 y. Two groups of girls were selected according to habitual calcium intake from a large group; one group consumed 1000-1304 mg/d (40th-60th percentile; n = 60) and the other group consumed <713 mg/d (<20th percentile; n = 50). Height, body weight, body fat, and calcium intake were measured at baseline and after 1 y.
At baseline a significant negative correlation was observed between habitual dietary calcium intake and percentage of body fat (r = -0.242, P = 0.011). However, calcium supplementation had no effect on height, body weight, or percentage body fat.
Habitual dietary calcium intake was inversely associated with body fat, but a low-dose calcium supplement had no effect on body weight, height, or body fat over 1 y in young girls. It is possible that the effect of calcium on body weight is only exerted if it is ingested as part of a meal, or the effect may be due to other ingredients in dairy products, and calcium may simply be a marker for a high dairy intake.
观察性研究积累的证据表明，高钙摄入量可能会降低体重和体脂。然而，很少有进行随机试验。
我们研究了补钙是否会影响年轻女孩的体重和体脂，以及习惯性钙摄入量与体重和体脂之间是否存在关联。
对(110)名年轻女孩进行了一项随机、双盲、安慰剂对照干预研究。受试者被随机分配接受(500mg)钙/天的碳酸钙或安慰剂，为期(1)年。从一大组女孩中根据习惯性钙摄入量选择两组；一组摄入(1000 - 1304mg)/天（第(40)至(60)百分位数；(n = 60)），另一组摄入(<713mg)/天（<第(20)百分位数；(n = 50)）。在基线和(1)年后测量身高、体重、体脂和钙摄入量。
在基线时，观察到习惯性膳食钙摄入量与体脂百分比之间存在显著负相关（(r = -0.242)，(P = 0.011)）。然而，补钙对身高、体重或体脂百分比没有影响。
习惯性膳食钙摄入量与体脂呈负相关，但低剂量补钙对年轻女孩(1)年以上的体重、身高或体脂没有影响。钙对体重的影响可能仅在作为膳食一部分摄入时才会发挥作用，或者这种影响可能归因于乳制品中的其他成分，而钙可能仅仅是高乳制品摄入量的一个标志。
